1. Drug discovery and drug design 2. Biological characterization 3. Early formulation studies 4. The investigational New Drug (IND) Application(研究性新药申请） 5. The New Drug Application (NDA)

Injections Small volume parenterals Large volume parenterals Special considerations associated with parenteral therapy Other injectable products-pellets or implants Irrigation and dialysis solutions

◼ Suspensions （混悬剂） ◼ Emulsions （乳剂） ◼ Gels and magmas （凝胶剂和乳浆剂） ◼ Proper administration and use of disperse systems （分散体系的正确给药和使用） ◼ Aerosols （气雾剂）

1. Solubility 2. Some Solvents for Liquid Preparations 3. Preparation of Solutions 4. Oral Solutions and Preparations for Oral Solution 5. Syrups 6. Elixirs 7. Tinctures 8. Proper Administration and Use of Liquid Peroral Dosage Forms 9. Topical Solutions and Tinctures 10. Vaginal and Rectal Solutions 11. Topical Tinctures 12. Topical Oral (Dental) Solutions 13. Miscellaneous Solutions 14. Nonaqueous Solutions 15. Extraction Methods for Preparing Solutions

1. Suppositories 2. Some factors of drug absorption from rectal suppositories 3. Suppository bases 4. Preparation of suppositories 5. Rectal suppositories 6. Vaginal suppositories 7. Packaging and storage 8. Vaginal inserts

I. Ointments II. Compendial requirements for ointments III. Creams IV. Gels V. Miscellaneous semisolid preparations: pastes and plasters VI. Features and use of dermatologic preparations VII. Features and use of ophthalmic ointments and gels VIII. Features and use of nasal ointments and gels IX. Features and use of rectal preparations X. Features and use of vaginal preparations

I. General principles of drug absorption II. Dissolution and drug absorption III. Bioavailability and bioequivalence IV. Routes of drug administration V. Fate of drug after absorption VI. Pharmacokinetic principles

I. The rationale for extended-release pharmaceuticals II. Terminology III. Extended-release oral dosage forms IV. Delayed-release oral dosage forms V. USP requirements and FDA Guidance for modified-release dosage forms VI. Clinical considerations in the use of oral modified-release dosage form VII. Packaging and storing modified-release tablets and capsules

1. The need for dosage forms 2. General considerations in dosage form design 3. Drug and drug product stability 4. Pharmaceutical ingredients

I. Powders II. Medicated powders III. Granules