外核膜可以看作是糙面内 质网的一个特化区域 紧贴内核膜内表面有 层致密的纤维网络结构, 即核纤层。内外核膜在 某些部位相互融合形成 环状开口,称为核孔 ( nuclear pore),核孔 Nuclear membrane consist of an inner 周围的核膜特称为孔膜 space between them, The outer 区( pore membrane membrane is occasionally continuous with domain the endoplasmic reticulum and is studded with ribosomes at the outside' surface
外核膜可以看作是糙面内 质网的一个特化区域。 紧贴内核膜内表面有一 层致密的纤维网络结构, 即核纤层。内外核膜在 某些部位相互融合形成 环状开口,称为核孔 (nuclear pore),核孔 周围的核膜特称为孔膜 区(pore membrane domain)。 Nuclear membrane consist of an inner and outer membrane with a perinuclear space between them. The outer membrane is occasionally continuous with the endoplasmic reticulum and is studded with ribosomes at the 'outside' surface
二)核被膜在细胞周期中的崩解与装配 个成熟的卵母细 胞所储存的原料 可供形成103~104 个细胞核 Interphase Nuclear envelope structure and function in living cells
(二)核被膜在细胞周期中的崩解与装配 一个成熟的卵母细 胞所储存的原料 可供形成103 ~104 个细胞核。 Nuclear envelope structure and function in living cells
核孔复合物( nuclear pore complex, NPC) 转录功能活跃的细胞,其 核孔复合体数量较多 Cytoplasm N_S-Bearng mport Substrate Fiaments <anchen Nudear Enve cge Karyopherin NES-Bagrino Export Substane Nucleus
二、核孔复合物(nuclear pore complex,NPC) 转录功能活跃的细胞,其 核孔复合体数量较多
Nudear membrane embedded in ice lear membrane embedded in ice partially freeze dried partially freeze dried
Nuclear membrane embedded in ice; partially freeze dried. Nuclear membrane embedded in ice; partially freeze dried
(一)结构模型 核孔复合物主要有以下4种结构 组分: Cytoplasmic Filament ①胞质环( cytoplasmic ring) Central Plug Cytoplasmic Ring ②核质环( nuclear ring)/核篮 Spake/ outer Nuclear (nuclear basket) Membrane ③辐( spoke) Lumen Nuelear 柱状亚单位( column subunit Inner Nuclear 腔内亚单位( luminal Nudear Ring Membrane subunit Baske Filament Nuclea 环带亚单位( annular Basket subunit Terminal Ring ④栓( central plug)/中央颗粒 (central granule Figure 3. A Cut-Away Model of an NPC
(一)结构模型 核孔复合物主要有以下4种结构 组分: ①胞质环(cytoplasmic ring) ②核质环(nuclear ring)/核篮 (nuclear basket) ③辐(spoke) 柱状亚单位(column subunit) 腔内亚单位(luminal subunit) 环带亚单位(annular subunit) ④栓(central plug)/中央颗粒 (central granule)