Questions to be addressed 1. How is the DNa mended rapidly enough to prevent errors from becoming set in the genetic material as mutation 2. How does the cell distinguish the parental strand from the daughter strand in repairing replication errors
Questions to be addressed 1. How is the DNA mended rapidly enough to prevent errors from becoming set in the genetic material as mutation 2. How does the cell distinguish the parental strand from the daughter strand in repairing replication errors
3. How does the cell restore the proper DNA sequence when the original sequence can no longer be read? 4. How does the cell deal with lesions that block replication?
3. How does the cell restore the proper DNA sequence when the original sequence can no longer be read? 4. How does the cell deal with lesions that block replication?
CHAPTER9 The mutability and repair of Na Topic 1: Replication errors and their repair 3/22/05 @博共字 Wuhan Universit
Topic 1: Replication errors and their repair CHAPTER 9 The mutability and repair of DNA 3/22/05
The nature of mutations Point mutations: 1. Transitions(pyrimidine to pyrimidine, purine to purine) 2. Transversions(pyrimidine to purine, purine to pyrimidine)
The nature of mutations Point mutations: 1. Transitions (pyrimidine to pyrimidine, purine to purine) 2. Transversions (pyrimidine to purine, purine to pyrimidine) Replication errors and replication
Insertions Deletions Gross rearrangement of chromosome These mutations might be caused by insertion by transposon or by aberrant action of cellular recombination processes
Insertions Deletions Gross rearrangement of chromosome. These mutations might be caused by insertion by transposon or by aberrant action of cellular recombination processes