Sandflies
Sandflies
Phlebotomus, sandfly Small, about 1/3 of a mosquito, 3mm, yellow-gray
Phlebotomus ，sandfly ▪ Small，about 1/3 of a mosquito, 3mm, yellow-gray
Life cycle Sandfly Stages Human Stages Sandfly takes a blood meal (injects promastigote stage Promastigotes are into the skin) phagocytized by Divide in midgut and migrate to proboscis Promastigotes transform into amastigotes inside macrophages A Amastigotes transform into promastigote stage in midgut Amastigotes multiply in cells (inchuding macrophages) of various tissues A ingestion of parasitized cell sandfly takes a blood meal
Life cycle
Life Cycle of leishmania spp sandfly human infection Promasti gotes bte dereloping in mid- transformaion to gut become needie only when fly feeds m certan diet pica&L· maJor ingestion by amati got macrophage I n skin macrophages : Q causing CUTANEOUS H/ LEISHMANIASIS Q L· donovan metastas izes to vIsceral (live marrow) causIng same parasites n VISCERAL LEISHMANIASIS peripheral blood transformator to L, braziliensis L。 mexIcana metastas I zes to nasal system or buccal ear causIng CHI CLERO ULCER cosa caus Ing MUCOCUTANEOUS LEISHMANIASIS
_________________________________________________________ Life Cycle of Leishmania spp
Life Cycle Promastigote Amasitgote Transformation
Life Cycle Promastigote Amasitgote Transformation