3. Balance of body water and sodium drink 1200ml water intake food 1000ml (2000-2500ml) oxidation 300ml balance of water urine 1200-1500ml water loss skin 500ml (2000-2500ml respiration 350ml feces 150ml Balance Intake/d 100-200mmol (digestive tract) of sodium Loss/d 100-200mmol (urinary system) ECF: 50% Distribution ICF: 10% of sodium骨基质:40%(正常血清钠:130-150mmo)
3. Balance of body water and sodium drink 1200ml water intake food 1000ml (2000-2500ml) oxidation 300ml balance of water urine 1200-1500ml water loss skin 500ml (2000-2500ml) respiration 350ml feces 150ml Balance Intake/d 100-200mmol (digestive tract) of sodium Loss/d 100-200mmol (urinary system) ECF:50% Distribution ICF: 10% of sodium 骨基质:40% (正常血清钠:130-150mmol)
()Regulation of osmotic pressure and volume Hypertonic thirst 1. body water// of ECF ADHt; aldosterone↓ sodium个 thirst AngI'ADH↑ body volume↓ aldosterone↑ receptor of volume e ADH↑ 2. body water f sodiun↓」ADH reabsorption of sodium I 3. blood volume →→ ANPt t aldosterone(ADS)↓ tension 4. others ADH↑ pain
(三) Regulation of osmotic pressure and volume Hypertonic thirst of ECF 1.body water ADH ; aldosterone sodium thirst Ang Ⅱ ADH body volume aldosterone receptor of volume ADH 2.body water sodium ADH reabsorption of sodium 3.blood volume ANP aldosterone(ADS) tension 4.others ADH pain
Figure: regulation ofaDH secretion oSmotic pressure R pressure r ADH volume r heart
Figure: regulation of ADH secretion osmotic pressure R pressure R ADH volume R heart
二、 water and sodium disorders hypertonic hypertonic dehydration isotonic water excess isotonic hypotonic hypotonic ()细胞外液容量不足( extracellular fluid deficit 1. Hypotonic dehydration sodium loss water loss serum sodium 130mmolL plasma osmotic pressure 280m0sm/L
二、water and sodium disorders hypertonic hypertonic dehydration isotonic water excess isotonic hypotonic hypotonic (一) 细胞外液容量不足(extracellular fluid deficit) 1. Hypotonic dehydration sodium loss ＞ water loss serum sodium ＜ 130mmol/L plasma osmotic pressure ＜ 280mOsm/L