Potassium disorders
Potassium Disorders
Preface: normal metabolism of potassium 1. normal serum potassium: 3.5-5.5mmol/L 2. distribution of potassium ICF: 98%(muscle: 75%) ECF: 20o 3. balance between intra-and extracellular k+ normal: 15 h 4. intake and loss of potassium intake: food: loss: urine: feces: sweat
Preface: normal metabolism of potassium 1. normal serum potassium: 3.5-5.5mmol/L 2. distribution of potassium ICF:98% (muscle:75%) ECF: 2% 3. balance between intra- and extracellular K+ normal: 15 h 4. intake and loss of potassium intake: food; loss: urine; feces; sweat
5. influencing facter of potassium homeostasis acidosis alkalosis porla serum insulin serum damage of cells IK+↑ADS IK↓ catabolism anabolism distal flow rate↓ distal flow rate t
5. influencing facter of potassium homeostasis acidosis alkalosis hypoxia serum insulin serum damage of cells [K+ ] ADS [K+ ] catabolism anabolism distal flow rate distal flow rate
I. Hypokalemia concept: serum potassium <3.5mmol/L 1. cause and pathogenesis ① intake I fast alkalosis injection of insulin 2 move into Barium poisoning cels hypokalemic periodic yI pe paralysis
I. Hypokalemia concept: serum potassium＜3.5mmol/L 1. cause and pathogenesis ① intake fast alkalosis injection of insulin ② move into Barium poisoning cells hypokalemic periodic paralysis
GI: vomiting; diarrhea; Gastrointestinal suction Skin: excessive sweats furosemide diuretic ③ losses diamox diuretic phase ofARF ren: pyelonephritis primary hyperaldosteronism lack of magnesium renal tubular acidosis
GI: vomiting; diarrhea; Gastrointestinal suction Skin: excessive sweats furosemide diuretic ③ losses diamox diuretic phase of ARF ren: pyelonephritis primary hyperaldosteronism lack of magnesium renal tubular acidosis