(2) Regulation by phosphorylation Interferon-丫 cell-surface receptor signal transduction process anus activated kinase两面神蛋白激酶 STATa signal transduction and transcription factor Phosphorylation at tyrosine residue homodimer 同源二聚体
(2)、Regulation by phosphorylation Interferon- cell-surface receptor signal transduction process Janus activated kinase 两面神蛋白激酶 STAT signal transduction and transcription factor Phosphorylation at tyrosine residue homodimer 同源二聚体
Interferon terferon JAK KI Phosphrylation○ +2ATP STATa monomers +2ADP Phosphorylated nuclear STATa dimer Response element
p p P p Interferon Interferon receptor JAK Kinase Unphosphrylation STAT monomers +2ATP +2ADP Phosphorylated STAT dimer Response element nuclear