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第三节 mRNA Processing, hnrnps and sn rnps 一、 hnrna 、pre- mRNAS 三、 hnrnp 四、 SnRNPs 五、 pre-mRNA processing
第三节 mRNA Processing, hnRNPs and snRNPs 一、 hnRNA 二、 pre-mRNAs 三、 hnRNP 四、 snRNPs 五、pre-mRNA processing
一、 hnrna eucaryotic rna pol ll transcribes a variety of different genes, from snrna genes of 60-300nt to the large antennapedia genes, whose genes can be over 100kb in length. The collection of these products is referred to as heterogeneous nuclear rna (hnrNa) 二、 pre-mRNAS These hnrNa are processed to give mRNAs called pre-mRNAS
一、hnRNA Eucaryotic RNA Pol II transcribes a variety of different genes, from snRNA genes of 60-300nt to the large Antennapedia genes, whose genes can be over 100kb in length. The collection of these products is referred to as heterogeneous nuclear RNA (hnRNA) . 二、pre-mRNAs These hnRNA are processed to give mRNAs called pre-mRNAs
o hnrnp: hetrogenenous nuclear ribonucleoprotein The hnrna is rapidly covered in proteins to form hnrNp The proteins involved have been classified as hnrna proteins A-U. These proteins are organized as a tetramer. Three copies of tetramer are combined with a rna molecule of 600-700nt, called hnrnp particles each particle has a size of 30-40S
三、hnRNP : hetrogenenous nuclear ribonucleoprotein The hnRNA is rapidly covered in proteins to form hnRNP. The proteins involved have been classified as hnRNA proteins A-U. These proteins are organized as a tetramer. Three copies of tetramer are combined with a RNA molecule of 600-700nt , called hnRNP particles, each particle has a size of 30-40S
The hnrNP protein are thought to help keep the hnrna in a single-stranded form and assist in the various rna processing reactions
The hnRNP protein are thought to help keep the hnRNA in a single-stranded form and assist in the various RNA processing reactions