Chapter 7 Translation Translation is the conversion of the information in the nucleic acid sequence to polypeptides of a specific amino acid sequence
Chapter 7 Translation Translation is the conversion of the information in the nucleic acid sequence to polypeptides of a specific amino acid sequence
Crick的中心法则 DNA DNA 1957年 transcription Reverse 1970年 transcription RNA RNA translation Protein Protein
Crick的中心法则 DNA 1957年 transcription RNA translation Protein DNA Reverse 1970年 transcription Protein RNA
Section 1 The three roles of rna MRNA template for protein synthesis mRNA carries information from dna in a triple codon 1. The genetic code has redundancy(多余 性, so codon is degenerate(简并的)
一、 mRNA: template for protein synthesis mRNA carries information from DNA in a triple codon 1. The genetic code has redundancy (多余 性), so codon is degenerate (简并的). Section 1 The three roles of RNA
1954年,G. Gamey对破译密码首先提出了设想 4 nucleotides taken 1 at a time could specified only 4 different amino acid Two nucleotides taken at a time would permit only 4 or 16 amino acids to be specified any 3 adjacent nucleotides create 64 possibl codon(4 ), a number more than enough to specify 20 different amino acids
4 nucleotides taken 1 at a time could specified only 4 different amino acid. Two nucleotides taken at a time would permit only 42 or 16 amino acids to be specified; Any 3 adjacent nucleotides create 64 possible codon (43 ), a number more than enough to specify 20 different amino acids 。 1954年, G. Gamov 对破译密码首先提出了设想
2 Features of genetic codons Stop codon UAA UAG UGA Start codon AUG UGG p 1 8 amino acids have more than one codon called synonymous codons(同义密码子). Generally they differ only in their third position In all cases, if the third position is pyrimidine, the codons specify the same AA. In most cases. if the third position is a purine, the codons are also synonymous
2 Features of genetic codons Stop codon UAA UAG UGA Start codon AUG Met UGG Trp 18 amino acids have more than one codon, called synonymous codons (同义密码子). Generally they differ only in their third position. In all cases, if the third position is pyrimidine, the codons specify the same AA. In most cases, if the third position is a purine, the codons are also synonymous