3. Functions of exudate:(l) Dilute local toxins →reduce the injury to tissue;(2) Bring in the nutritional substance for leukocytescarry off the metabolic products in infla foci(3)kill thepathogen:Ab, complement.(4)Fibrinmesh:limit the spreading of pathogenic organismslimittheremoving of Mprepairframe.(5)Organisms-LN:benefit to producing of immune
3. Functions of exudate: (1) Dilute local toxins →reduce the injury to tissue; (2) Bring in the nutritional substance for leukocytes carry off the metabolic products in infla foci. (3) kill the pathogen : Ab, complement. (4) Fibrin mesh: limit the spreading of pathogenic organisms limit the removing of Mφ repair frame. (5)Organisms LN:benefit to producing of immune
三.Leukocyte extravasationandphagocytosis1. Leukocyte extravasation: leukocyte passthrough vascular wall into the site of injury.Divided into following steps:Margination and rollingAdhesionEmigration and chemotaxis
三. Leukocyte extravasation and phagocytosis 1. Leukocyte extravasation: leukocyte pass through vascular wall into the site of injury. Divided into following steps: Margination and rolling Adhesion Emigration and chemotaxis
(1) Margination and rollingleukocytein central axial columnBV dilation, speed of blood flowlmarginationrollingpavementingappearance
(1) Margination and rolling leukocyte in central axial column BV dilation, speed of blood flow↓ margination rolling pavementing appearance
Leukocytic emigration粘着边集滚动游出损伤部位（化学刺激物）趋化作用
Leukocytic emigration
(2)Adhesion:DBybinding of complementary adhesionmolecules on the leukocyte and endothelialsurfaces2)Adhesion molecules:The immunoglobulin family: I(VCAM-1Integrins:aandβchains
(2) Adhesion: 1) By binding of complementary adhesion molecules on the leukocyte and endothelial surfaces 2) Adhesion molecules : The immunoglobulin family: I(V)CAM-1 Integrins:αand βchains