Organic Chemistry,6th Edition L.G.Wade,Jr. Chapter 25 Amino Acids Peptides and Proteins
Chapter 25 Amino Acids, Peptides and Proteins Organic Chemistry, 6th Edition L. G. Wade, Jr
Key points Classification of amino acids Preparation of amino acids Reactions of amino acids ■peptides Classification and structure of proteins 蛋白质 较复杂的含氮生物有机大分子， 是生物体内一切细胞的重要组成 部分，是生命的重要物质基础 氨基酸 组成蛋白质的基本成分
Key points ◼Classification of amino acids ◼Preparation of amino acids ◼Reactions of amino acids ◼peptides ◼Classification and structure of proteins 蛋白质 较复杂的含氮生物有机大分子， 是生物体内一切细胞的重要组成 部分，是生命的重要物质基础 氨基酸 组成蛋白质的基本成分
Sec 1:Classification and stereochemistry of amino acids ■Standard Amino Acids OTwenty standard a-amino acids. .Differ in side-chain characteristics: >-H or alkyl >contains an -OH >contains sulfur >contains a nonbasic nitrogen >has -COOH >has a basic nitrogen
Sec 1: Classification and stereochemistry of amino acids ◼Standard Amino Acids ⚫Twenty standard -amino acids. ⚫Differ in side-chain characteristics: ➢-H or alkyl ➢contains an -OH ➢contains sulfur ➢contains a nonbasic nitrogen ➢has -COOH ➢has a basic nitrogen
Essential Amino Acids ■Arginine(Arg精)！ Tryptophan(Trp色) ■Threonine(Thr苏)Methionine(Met蛋) Lysine(Lys赖) ■Histidine(His组) Valine(Val缬) ■Leucine(Leu亮) Phenylalanine ■Isoleucine(Ile异亮) (Phe苯丙)
Essential Amino Acids ◼Arginine (Arg 精) ◼Threonine (Thr 苏) ◼Lysine (Lys赖) ◼Valine (Val 缬) ◼Phenylalanine (Phe苯丙) ◼Tryptophan (Trp色) ◼Methionine (Met 蛋) ◼Histidine (His组) ◼Leucine (Leu亮) ◼Isoleucine (Ile异亮)
Complete Proteins Provide all the essential amino acids. Examples:those in meat,fish,milk,eggs. Plant proteins are generally incomplete. Vegetarians should eat many different kinds of plants,or supplement diet with milk or eggs
Complete Proteins ◼Provide all the essential amino acids. ⚫Examples: those in meat, fish, milk, eggs. ◼Plant proteins are generally incomplete. ◼Vegetarians should eat many different kinds of plants, or supplement diet with milk or eggs