Respiratory failure Zhang Xiao-ming Dept pathophysiology
1 Respiratory Failure Zhang Xiao-ming Dept. pathophysiology
ANATOMY OF THE LUNG Bronchi Trachea Capilla BLood Back to Heart Bl From The Heart Intrapleural g space Alveolus
3
RESPIRATION 4 distinct mechanisms: Ventilation Gas exchange J External respiration Transport of oxygen and carbon dioxide in the ood Internal respiration
4 RESPIRATION 4 distinct mechanisms: Ventilation Gas exchange External respiration Transport of oxygen and carbon dioxide in the blood Internal respiration
The Process of External respiration PiO 159mmH Pulmonary ventilation PO, 102mImH PACO2 40mmHg Pulmonary gas exchange Pao,40mmHg PaCo2 46mmHg PyO 100mmhs g PvCO, 40mmHg
5 The Process of External Respiration Pulmonary gas exchange PiO2 159mmHg PAO2 102mmHg PACO2 40mmHg Pulmonary ventilation PaO2 40mmHg PaCO2 46mmHg PvO2 100mmHg PvCO2 40mmHg
Definition of re Disorders of external respiratory function Pa02<60 mmHg(8.0kpa) while breathing air at rest, with or without Paco2 >50 mmHg (6.67 kpa). judgment standard: Pao2 <60 mmHg, Paco2 >50 mmHg hypotonic hypoxia with(or without) respirator acidosis 6
6 Definition of RF Disorders of external respiratory function PaO2 <60 mmHg (8.0kpa) while breathing air at rest, with or without PaCO2 >50 mmHg(6.67kpa). judgment standard: PaO2 <60 mmHg , PaCO2 >50 mmHg hypotonic hypoxia with (or without) respiratory acidosis