E Organic chemistry experiment The synthesis of DBa Experimental center of chemical education Fudan University
The synthesis of DBA Experimental center of chemical education Fudan University Organic chemistry experiment
Target 1. Master the principle of aldol reaction 2. Obtain the product through controlling the ratio of starting materials
1.Master the principle of aldol reaction. 2.Obtain the product through controlling the ratio of starting materials. Target
Background Pd,( dba)3 is a good source of pd(o) which is widely used as a catalyst in cross coupling -Pd ---Pd
Pd2 (dba)3 is a good source of Pd(0) which is widely used as a catalyst in cross coupling. Background
迫 Experimental principle 1.Two molecule of carbonyl compounds with a-H. can condense to form B-hydroxy aldehyde(ketone). While rasing the reaction temperature, will form further form a, B unsaturated aldehyde(ketone) 2. A non-aH aromatic aldehyde can condense with carbonyl compounds containing a-h to form o, B-unsaturated aldehyde (ketone), it is so-called Clasien-Schmidt reaction
1.Two molecule of carbonyl compounds with α-H, can condense to form β-hydroxy aldehyde(ketone). While rasing the reaction temperature, will form further form α,β- unsaturated aldehyde (ketone). 2. A non- α-H aromatic aldehyde can condense with carbonyl compounds containing α-H to form α,β-unsaturated aldehyde (ketone), it is so-called Clasien-Schmidt reaction. Experimental principle
NIV 迫 Experimental principle H2O OH O
Experimental principle