David chen 11307120002 STRESS ANR SERQTONIN SYSTEM
STRESS AND SEROTONIN SYSTEM David Chen 11307120002
WHAT IS SEROTONIN x Neurotransmitter(神经递质) x Also called5 hydrotrptamine(5HT)5羟色胺 x Synthesized from tryptophan
WHAT IS SEROTONIN? Neurotransmitter(神经递质) Also called 5-hydrotrptamine(5-HT)5-羟色胺 Synthesized from tryptphan
HOW ROES THIS SYSTEM ORK &Q (pre-v 501A 5-HT1B-R post-synaptic pre-synaptic MAOA neuron serotonin neuron degradation 5-HT1A-R ontogeny TPH1 VMAT2 H2-mediated 5-HT2C-R PET-1 i transport SERT synthesis→ 5-HT3A-R MAOA 5-HT1A-R SERT reuptake 5-HT2A-R 5-HT1A-R Fig from Genetic variation in cortico-arhygdala serotonin function and risk for stress- related disease
HOW DOES THIS SYSTEM WORK? Fig. from Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
RISTRIBUTION OF SEROTONERGIC NEURONS IN OUR BRAIN mPFC mPFC内侧前额叶 DRN Amygdala杏仁体 DRN中缝背核 5-HT1A-R 5-HT1B-R amygdala 5-HT2A-R 5-HT2C-R M 5-HT3A-R Fig from Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
DISTRIBUTION OF SEROTONERGIC NEURONS IN OUR BRAIN Fig. from Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease mPFC内侧前额叶 Amygdala杏仁体 DRN中缝背核
RELATION BETWEEN SEROTONIN AND STRESS x Exposure to stressors. serotonin neuron activity is increased Excerpted from Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus x...at all levels of the serotonin system.can influence. the response to stress x-Excerpted from Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
RELATION BETWEEN SEROTONIN AND STRESS Exposure to stressors … serotonin neuron activity is increased… --Excerpted from Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus …at all levels of the serotonin system…can influence … the response to stress. --Excerpted from Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease