Acute Renal Failure. ARF
Acute Renal Failure, ARF
Definition Etiology classification Prerenal failure Intrinsic renal failure Post(obstructive renal failure Pathogenesis Clinical manifestation Therapy
• Definition • Etiology & classification Prerenal failure Intrinsic renal failure Post(obstructive) renal failure • Pathogenesis • Clinical manifestation • Therapy
Definition Acute renal failure (arf) is defined as a precipitous and signif icant (50%)decrease in glomerular filtration rate(GFR)over a period of hours to days, with an accompany ing accumulation of nitrogenous wastes in the body
Definition • Acute renal failure (ARF) is defined as a precipitous and significant (>50%) decrease in glomerular filtration rate (GFR) over a period of hours to days, with an accompanying accumulation of nitrogenous wastes in the body
急性肾功能袞竭的定义 急性肾功能衰竭( acute renal failure,ARF)是指各种病 因引起双侧肾脏在短期内泌尿功能急剧隆低,导致机体内环境 出现严重紊乱的病理过程和临床综合症。 肾泌尿功能障碍表现为GFR迅速下降,出现少尿无尿;内 环境紊乱主要表现为氮质血症、高钾血症和代谢性酸中毒。 急性肾功能衰竭根据尿量减少与否,分为少尿型(成人每 日尿量少于400m)和非少尿型(成人每日尿量大于400m) 两种类型。急性肾衰病情凶险,临床较常见,但若及时诊治, 预后较好
急性肾功能衰竭的定义 急性肾功能衰竭（acute renal failure，ARF）是指各种病 因引起双侧肾脏在短期内泌尿功能急剧降低，导致机体内环境 出现严重紊乱的病理过程和临床综合症。 肾泌尿功能障碍表现为GFR迅速下降，出现少尿无尿；内 环境紊乱主要表现为氮质血症、高钾血症和代谢性酸中毒。 急性肾功能衰竭根据尿量减少与否，分为少尿型（成人每 日尿量少于400ml）和非少尿型（成人每日尿量大于400ml） 两种类型。急性肾衰病情凶险，临床较常见，但若及时诊治， 预后较好
Etiology o Pre-renal (% of cases) resulting from impaired blood flow to or oxygenation of the kidneys o Intrinsic-renal (25% of cases) resulting from injury to or malformation of kidney tissues o Post-renal (<5% of cases) resulting from obstruction of urinary flow between the kidney and urinary meatus
Etiology Pre-renal (~70% of cases) resulting from impaired blood flow to or oxygenation of the kidneys. Intrinsic-renal (~25% of cases) resulting from injury to or malformation of kidney tissues. Post-renal (<5% of cases) resulting from obstruction of urinary flow between the kidney and urinary meatus