2.Morphological and biochemical characteristics of apoptosis Morphological changes: Initiation:Chromatin condensation,cell body shrink; Apoptotic bodies:Chromatin fragmentation,along with some organelles be wrapped by membranes and blebbing from the cells; Phagocytosis:apoptosis bodies be phagocytized by other cells. Mild convolution Nuclear Chromatin fragmentation compaction and Blebbing Apoptotic Phagocytic segregation body cell Condensation of Cell fragmentation cytoplasm Phagocytosis This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
3.Significance of apoptosis Proliferation (mitosis) Increasing Cell number Cell number balance Apoptosis Decreasing Cell number 7 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
3.Significance of apoptosis Involved in developmental process; Remove unnecessary cells(damaged,infected cells). Aberrant apoptosis: Hyper-:defective immune reaction,many degenerative changes; Hypo-:tumor,autoimmune disease. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
3.1 Apoptosis during the metamorphosis of a tadpole into a frog This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
3.2 Sculpting the digits in the developing mouse paw by apoptosis (A) (B) 1mm 10 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information