Unintentional or Incidental Chemical Contaminants > Agricultural chemicals (e.g.,pesticides, fungicides,herbicides,fertilizers,and other residues) >Prohibited substances Toxic elements/compounds (e.g.,lead,tin, copper,zinc,arsenic,mercury,cyanide)
Unintentional or Incidental Chemical Contaminants Agricultural chemicals (e.g., pesticides, fungicides, herbicides, fertilizers, and other residues) Prohibited substances Toxic elements/compounds (e.g., lead, tin, copper, zinc, arsenic, mercury, cyanide)
Unintentional or Incidental Chemical Contaminants (cont'd) Cross-contaminating food allergens from inadequately cleaned shared processing equipment >1 Processing plant chemicals(cleaners, sanitizers unapproved lubricants)
Cross-contaminating food allergens from inadequately cleaned shared processing equipment Processing plant chemicals (cleaners, sanitizers & unapproved lubricants) Unintentional or Incidental Chemical Contaminants (cont’d)
Intentionally Added Chemicals Food Additives >Direct(allowable limits under cGMPs) >Preservatives (e.g.,sulfiting agents) >Nutritional additives (e.g.,calcium,niacin) >Color additives
Intentionally Added Chemicals – Food Additives Direct (allowable limits under cGMPs) Preservatives (e.g., sulfiting agents) Nutritional additives (e.g., calcium, niacin) Color additives
Intentionally Added Chemicals Food Additives (cont'd) Indirect Packaging r materials >Processing plant chemical > Lubricants(food grade) > Sanitizers
Intentionally Added Chemicals – Food Additives (cont’d) Indirect Packaging materials Processing plant chemical Lubricants (food grade) Sanitizers
INTENTIONAL ADDITIVES Niacin(Vitamin B3)routinely used to enrich grain products to prevent pellagra ×RDAs:10-20mg x Can cause a chemical intoxication if used in excessive amounts
Niacin (Vitamin B3 ) routinely used to enrich grain products to prevent pellagra RDAs：10-20mg Can cause a chemical intoxication if used in excessive amounts