Sec 2 Structure and configuration of sacchrides ■D and L Sugars Cyclization of Monosaccharides ■Cyclic Structure ■Haworth Projections Conformational Formulas CHO CHO : H-COH CH2OH CH2OH (R)-Glycer- (S)-Glycer- aldehyde aldehyde
Sec 2 Structure and configuration of sacchrides ◼D and L Sugars ◼Cyclization of Monosaccharides ◼Cyclic Structure ◼Haworth Projections ◼Conformational Formulas
Structure and configuration of sacchrides OD sugars can be degraded to the dextrorotatory (+ form of glyceraldehyde. L sugars can be degraded to the levorotatory(-) form of glyceraldehyde. CHO CO2 H一C一OH CHO C02↑ HO-C-H degrade HO C一H degrade CHO CO2t H-C-OH H C- OH H一C一 OH CHO H-( C OH H C一OH H一C一 OH degrade H一C一OH CH2OH CH,OH CH,OH CH,OH D-(+)-glucose D-(-)-arabinose D-(-)-erythrose D-(+)-glyceraldehyde L--编号最大的手性碳决定； 天然存在的糖大多数都是D一型糖
Structure and configuration of sacchrides ⚫D sugars can be degraded to the dextrorotatory (+) form of glyceraldehyde. ⚫L sugars can be degraded to the levorotatory (-) form of glyceraldehyde. D L---编号最大的手性碳决定； 天然存在的糖大多数都是D－型糖
Erythro and Threo 赤式&苏式 Terms used for diastereomers with two adjacent chiral C's,without symmetric ends. For symmetric molecules,use meso or d CH2CH3 CH2CH3 COOH COOH H Br Br H H OH H OH H Br H Br H OH HO H CH3 CH3 COOH COOH erythro threo meso (±)or(d,l) 2,3-dibromopentane tartaric acid =>
Erythro and Threo 赤式 & 苏式 ◼Terms used for diastereomers with two adjacent chiral C’s, without symmetric ends. ◼For symmetric molecules, use meso or d,l. =>
The D Aldose Family CHO H-OH CHOH D-(+)-glyceraldehyde CHO CHO H -OH HO- H H-OH H-OH CH,OH CH,OH D-(-)-erythrose D-(-)-threose CHO CHO CHO CHO H OH HO H H -OH HO -H H OH H OH HO -H HO H H- OH H OH H -OH H -OH CH OH CH OH CHOH CH OH D-(-)-ribose Y YD-(-)-arabinose D-(+)-xylose D-(-)-lyxose CHO CHO CHO CHO CHO CHO CHO CHO H -OH HO- -H OH HO H H OH HO H H-OH HO H H- OH H OH HO H HO H H OH H OH HO ..Ho H H OH H- OH OH OH HO H HO- HO- HO H-OH H -OH H- -OH H OH H- 一OH H-OH H-OH H OH CHOH CH,OH CH,OH CH,OH CH,OH CH,OH CH,OH CH,OH D-(+)-allose D-(+)-altrose D-(+)-glucose D-(+)-mannose D-(-)-gulose D-(-)-idose D-(+)-galactose D-(+)-talose
The D Aldose Family
Prsphate esters of huctose py ajor role in glycol sis