国内化学期刊Acta Chimica Sinica《化学学报》ChineseJournalofChemistryChineseChemicalLetters,CCL中科院双月刊2022IF:23.178NationalScienceReviewNSR中科院+基金委月刊2021IF：10.138Science China Chemistry2020年创刊季刊（EIsevier）GreenSynthesisandCatalysis发表文章数量少，国内学者居多微信公众平台X-MOL资讯；CBG资讯；Chem-Station(化学空间)；化学人生；化学加
国内化学期刊 微信公众平台 X-MOL 资讯；CBG资讯； Chem-Station(化学空间)； 化学人生；化学加 Acta Chimica Sinica 《化学学报》 Chinese Journal of Chemistry Chinese Chemical Letters, CCL National Science Review NSR 中科院 双月刊 2022 IF:23.178 Science China Chemistry 中科院+基金委 月刊 2021 IF:10.138 Green Synthesis and Catalysis 2020年创刊 季刊 (Elsevier ) 发表文章数量少，国内学者居多
Organic LettersScheme 2, Scope of Cyclobutanone Oxime EstersScheme 4. Synsthesis of 3a on a Gram Scale 1Organic LettersLeterCyanoalkylation of Benzothiazoles and Caffococh2010,75,5768 (C) CheBa, WAihS.Catal2010,352, wococnScheme S. Proposed MechanismsY9Ss (d)Li,Z.S,WangW.X,Yang J-D,Wu,Y-W+ZhangW.2HhsX*MeCN,100*C,NOrg Lea.2013, 5,3820. () Ga,PGaYRDun,X-H.Soet2Cas432017, 49, 3407.2161"(3)(a)Nikam SSSabasrabudhe,ADShastsiRKy2TLMmeNet1Ramanathan, S.Sythos 1983,1983, 145.(b)LawrenouNe,D.S28ococCopeJE;Smith,CD.JMdChom2001,44,04,(e)udiloaeHON2N,KooVBib,WFeKEhr,KNo,e40.7054,8%.HLBiockem Phenacol2003,65, 59. (d) Qin,XHo,X,Ha, H, aZgWuBHuann+Jing4SRYYZom,CMd.Chm.2015S.1254.()HY.Y.WaZJias7oco0fXYunWC.TetruhoLt2010,,2023.(0Ce2hang X-M;YsA;Brion, JDMessuoudi,S:Alami,MOg Let 2013,155606.2,%.804t75OTBOPSoIn summary,wehave developed an efficient Fe-catalyed(g)Yin,K,Zhang,R-H.rgLet.2017,9,1530 (h)PautS,Ha,JYOYeH,Pad,G.E,Lee,Y.R.Adn Syot.Catal.2017,359, 1515. (0 Yuan,mes cyanoallylation reaction of quinotalin-2(1H)-ones with cycloa人J-W,LiS-N,Q,L-B.A.Synht Catul2017,39,4197. ()Gaie butanone oxime esters,This neaction features wide substrate?us. 2016, 52, 229win, R, Cu, X-L Ches Cine scope, excellent functional group tolerance,and good to68%yieldrespectively3-Cyanollylated846 (k)Li,YiGao,MjWangL-HaCui, X-LOrgBiomalChem.20mexcellentyieldsthus providingfacileandusefiulaccesstoobtained in 49% yield under the modified con2016, 14, 8528 (I) Gupta, A, Deshmukh, M Sa Jain, N. J. Org Chem 2)172 variety of 3-cyanollylated quinoxalin-2(1H)-ones. BesidesoXFinally, ceveral enntrnl eperimente were pi201782.4784(m)ZengX-BLiu.C.LWangX.Y2hangJ-L/23?ms cyclobutanone axime esters, the cyclopentanone and cyclo.福X-Y Hu, Y.F.Org Bieme. Chem 2017, 13, 8929insight into the reaction mechanisns, Radical2hecanonedkcivatives werealsoapplicabketothisrcaction.Thia4E.F.Net.Prud Rp.199, 10, 397. (b) May,L.LJ24(4) (a) Herments were conducted first by adition ofTE]4.T17s protocol offers anew and promising family of direct CHJabon, AE, Mmoe, MV, Traer, J,R, Woode,jL Ha, the reaction of ila and 2a, respectively (egs 1irs functionalizations of heteroarenesbased on a C-C bondSyBouman,ER, Aceto, MD..MedChom 20o, 3,5030,Pcoc177 deavage processPreliminary mechanistic evidence suggests(c) Fleming, F.Fa Yao, L, Ravkumar, P. C, Funk, L, Shook, B. C.J. 2o0oCAFe5074005 17s that the cyanoalkylation reaction proceeds via a radicalMof.Chem,2010, S3,7902.2283O,C.N(S) For revieus, see: (a) Fleming F, F> Zhang Z-Y. Torualm 2TEUPDaS pathway.I02005, 6l, 747. (b) Lpez, R, Palomo, C. Agnz. Clmm, It. Ed. 2015, 24eta2na$4, 13170241180-ASSOCIATED CONTENT()eee)ouQs Supporting InformationScheme 3. Ring Opening of Cyclopentanone andChom Commun 2015, 51, 969. (b) Buneson,A, Wang, Q; Zhu,J.231180m The Supporting Informationsavailablefeeof charge on theAngo.Chom, Int, Ed.2015, 54, 3132. (c) Chutalova-Suepin.ChCydlohexanone Orime Esters2WangQSammis,G.MZhu.JAngnv.Chon, nt Ed.2015,4,.m ACS Publlcationa website at DO1: 10.1021/acs.or.0sPS443. (d) Bunesct A;Wang QZhm,JOng Lant 2015,17,1890,246glet.7b03984.oxsYAC(e)Ha,.M;Chtalova-Saepin,C;WangQ;Zhu,J.Angn.Chom,aExperimenal procedures and spectroscopic data for pew185a:int Ed.2016, 55, 9249. (0 Chu,XQ;Xing Z.H,Meng H, Xu,X-sW-ococs2186compounds (PDF)P,J.S.J.OrgChmFrout2016.3,165.(g)ZhangH.L,ZhuCJ.*oaamo.Org Chem.Frem,2017.4,1272. (h) Su,H.MWang L-Y;Ra H250goAUTHORINFORMATION服中8H; Xu, H. Org Lelf. 2017, 19, 22262$1(7)Foreamplesconoeing radicalringepeningofcyclobutanoeehiss Corresponding Authoroatmstivse(a)BonJoZadAws*Email guoln81@xitu.edu.cn.:ChmSoc1991,113,5. (b)Boiin,J:Fouqot,E+Zand,o3eORCIDTetrahefrn Lett, 1991, 32, 4299. (c) Nishimura, T. Yoshinaka, T.) 58nta. c. wr tonohiguch,Maeda,YUemura SOrgLett2005,24251541 19s LNa Guo: 000-002-9789-69520000m(d)ngH-BSelnde,.Chom.ur.2017,24179. (Zhao,EmNotesB, Sh, Z. Angow. Chem, lar.EA 2017, 56, 12727. (0 LL, L-Y. Chen, t180EsH-GuMelMJZhou, LoChen Cames2017, $3, 115+4, 259of TEMPO (1.0equs) significantly suppresesTheauthos dedarenocompeting finncial interest.A(g) Yang H-B; Pathipati, S. R; Selander, N, ACS Catal 2017, 7, olation reaction, and the cyanoallyl-TEMPO8441. (h) Dauncey, E. Mj Morcilo, S P, Douglas, J. Ja Sheikh, N,S t600eseonChm87(0)YCequiv) also led to anobrsous decrease in th ws Financial suppont from the NatwalScience Basic Research PlanJ-R, Wang P.Z, Yang M-N, Liang D Xiao, W.. Ango. Chom,263DCL.NThese results indicate that radical intemediate ise in Shand Province of China (2016yz002),the NationalInt.Ed 2018, 57, 738. (0) Jadman,MM; Im, S, Bohman,S. R, Lo, 42thistransfomationOntheotherhandNaturalScenceFoundationofChina(21602168),ndtheCCGaityACastle,ChmEr.21824,94265ta66, 154periments were designed and peformed mFundamemtal Research Fundsof the Central Ueiversti(8) For palladium-catalyved ring opening of cyclobutanone oxime 26see: (a) Nshimura T, Uemura, S. J.Am, Chem.Soc.2000, 122, gclobtanonemmeeters12and 1bc(and2017001j2016056and1191329724)greatly12049. (b) NishenNiiMg2e apprecizted.bonds with la delivered the ring-closing prodtChomL 2004, 69, 5342.aie cyclohexanoneoxime esters 5c and sd, FeSO,7H,O gavein3%and65%d,repectively (g ad(9) (a) Gu, Y.R; Duan, X.H, Yang L; Guo, L-N: Org Left 2017, 2n0服REFERENCES211u better yields than Fe(acac)2.are in favor of radical pathway for this(1) (a) Res,U.JPriepke,W,MHauel, NHHandsch,To further demonstnte the applicabitity of this cymoulkylaHowever, the spirocyclic substrate 12c affeChom.,2018, 83 1046.132MGJMWnWNHBogMCh(10) For more detailks, see the Supporting nforimation.13e in 89% yield with no ring-epanded prodh133 tion reaction, a gram-scale reaction was carried out under the3N 2003, 13, 2297. (b) Carta, A; Puras, S; Loriga, G, Paglie, G, Me13 standard conditions (Scheme.4),. Satisfactorily, the reaction of5), A possible mechanism is proposed in 20s Rer. Mod. Chem. 2006, 6, 1179. (e) L, X,Yang K, L Wy Xu, W.lus la and 2a proceeded smoothly to afford the target product 3aingconconfye()Fu2(a)iHungM1e in 80% isolated yield. Furthermore, the C-H bonds ofL,which istransfomed intocyanalky radicalanGo,X-YLiG.MedChen20lS4,5747. (e)Husainbond ceavage,Subequently,radical additionas Paen,S; Hao,X,Zhang S-Z., Wang W, Qin,X.YYang Y-Cas benzothiazole and cafeine could also be directly cymoalkylatedodicldawhchunghZZJh)s by using Fe(OTf), instead of Fe(acac) as the catalyst.Cowidation byFe() fllowed by lossoe3833s Treatment of benzothiazoles 7a and 7b with 2a gave them (2) (a) Mamedov_ V. A, Zhukow, N: A. Prog_ Heerogd. Chem.14e corresponding 2-cynoalkylated products 8a and sb in 69% andproduct 3a.212 2012, 24, SS, (b) Chen, D, Wang Z.-Js Bao, W.L J. Org Chon0Coisiiaciagetnaine
作业一：选择自已所在研究领域的论文一篇。撰写文献笔记。1.论文属性是研究论文还是综述。2.文章的结构：分为哪几部分，各部分描述了什么内容。3．本研究工作针对什么问题开展了研究，创新点是什么，研究方法包括哪些？4.本研究的不足是什么，如果你来做这个研究工作，将如何改进？5.文献阅读中注意专业词汇的积累。养成用词严谨的习惯。列出5个以上专业词汇
作业一：选择自己所在研究领域的论文一篇。撰写文献笔记。 1. 论文属性是研究论文还是综述。 2. 文章的结构：分为哪几部分，各部分描述了什么内容。 3. 本研究工作针对什么问题开展了研究，创新点是什么，研究方法 包括哪些？ 4. 本研究的不足是什么，如果你来做这个研究工作，将如何改进？ 5. 文献阅读中注意专业词汇的积累。养成用词严谨的习惯。 列出 5个以上专业词汇
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高等有机化学Advanced Organic Chemistry任课教师郭丽娜：从事有机合成、催化不对称合成等办公室：19#-4129室Email:guoln81@xjtu.edu.cn授课方式：PPT多媒体授课课时：（2-9周）周三（3-4节、5-6节）19-3110考核过程考核30%（考勤、大作业）+闭卷考试70%资料：讲义+PPT
高等有机化学 Advanced Organic Chemistry 任课教师 郭丽娜： 从事有机合成、催化不对称合成等 Email：guoln81@xjtu.edu.cn 办公室：19 #-4129 室 授课方式：PPT多媒体授课 课 时：（2-9周）周三（3-4节、5-6节） 19-3110 考 核 过程考核30%（考勤、大作业） +闭卷考试70% 资 料：讲义+PPT