Colorants and flavorants 应符合药用规格,口服所用色素必须是 药用级或食用极 色素最大用量一般不超过005% 把色素先吸附于硫酸钙、三磷酸钙、淀 粉等主要辅料中可有效地防止颜色的迁 移 香精的加入方法是将香精溶解于乙醇中 均匀喷洒在已经干燥的颗粒上
Colorants and flavorants • 应符合药用规格，口服所用色素必须是 药用级或食用极 • 色素最大用量一般不超过0.05% • 把色素先吸附于硫酸钙、三磷酸钙、淀 粉等主要辅料中可有效地防止颜色的迁 移 • 香精的加入方法是将香精溶解于乙醇中， 均匀喷洒在已经干燥的颗粒上
2) Multiply compressed tablets Multiply compressed tablets are prepare y subjecting the fill material to more than a single compression Layered tablets are prepared by initial compaction of a portion of fill material in a die followed by additional fill material and compression to form two- or three layered tablets, depending on the number of separate fills
2) Multiply compressed tablets • Multiply compressed tablets are prepared by subjecting the fill material to more than a single compression. • Layered tablets are prepared by initial compaction of a portion of fill material in a die followed by additional fill material and compression to form two- or threelayered tablets, depending on the number of separate fills
3)Sugarcoated tablets Compressed tablets may be coated with a colored or an uncolored sugar ayer. The sugarcoat protects the enclosed drug from the environment and provides a barrier to objectionable taste or odor The sugarcoat also enhances the appearance of the compressed tablet
3) Sugarcoated tablets • Compressed tablets may be coated with a colored or an uncolored sugar layer. • The sugarcoat protects the enclosed drug from the environment and provides a barrier to objectionable taste or odor. • The sugarcoat also enhances the appearance of the compressed tablet
Disadvantages: The time and expertise required it the coating process and the increase in size, weight, and shipping costs
Disadvantages: The time and expertise required in the coating process and the increase in size, weight, and shipping costs
4)Film-coated tablets Film-coated tablets are compressed tablets coated with a thin layer of a polymer capable of forming a skin like film over the tablet The film is usually colored and has the advantage over sugarcoating in that it is more durable, less bulky and less time consuming to apply
4) Film-coated tablets • Film-coated tablets are compressed tablets coated with a thin layer of a polymer capable of forming a skinlike film over the tablet. • The film is usually colored and has the advantage over sugarcoatings in that it is more durable, less bulky, and less time consuming to apply