LM Red cells lysed Fibrinous exudate and neutrophils within alveoli No pneumococci detected 心 这? eleNE △ Clinical features same as red hepatization purulent sputum hypoxia improved
26 LM — Red cells lysed — Fibrinous exudate and neutrophils within alveoli — No pneumococci detected Clinical features same as red hepatization purulent sputum hypoxia improved
IV Resolution GI ross Pleural resolved or organized fibrous thickening LA or permanent adhesions Exudates within alveoli enzymatically digested Either resorbed and ingested by macrophages or expectorated △ Clinical features Recovery 原
27 IV Resolution Gross — Pleural resolved or organized fibrous thickening or permanent adhesions LM — Exudates within alveoli enzymatically digested Either resorbed and ingested by macrophages or expectorated Clinical features Recovery
Remarks 1.In the era before antibiotics, lobar pneumonia evolved through four stages 2. Early antibiotic therapy alters or halts this typical progression. The anatomic changes seen at autopsy may not conform to the classic stages
28 Remarks 1.In the era before antibiotics, lobar pneumonia evolved through four stages. 2. Early antibiotic therapy alters or halts this typical progression. The anatomic changes seen at autopsy may not conform to the classic stages
Complications Not common; Death rate:3-5% ^ Carnification(肺肉化, organing pneumonia) A Pulmonary abscess and pyothorax A Septicemia ∵数 ▲ Toxic pneumonia 1 Organized by fibroblasts growing into it. Organization of the intra- alveolar exudate may convert areas of the lung into solid fibrous tissue. i
29 Complications Not common; Death rate: 3 ~ 5 % Carnification (肺肉化, organizing pneumonia） Pulmonary abscess and pyothorax Septicemia Toxic pneumonia Organized by fibroblasts growing into it. Organization of the intraalveolar exudate may convert areas of the lung into solid fibrous tissue
Carnification
30 Carnification