UNIV Zabeuawlileirady Peripheratneuropatl: rigid and swollen nerves From small dermal nerves to nerve trunk N. auricularis magnus(耳大) N. auricularis posterior(耳后) LM Granulomatous inflammatory reactions Fibrosis, absence of nerves
Tuberculoid leprosy Peripheral neuropathy: rigid and swollen nerves From small dermal nerves to nerve trunk N. auricularis magnus (耳大)， N. auricularis posterior(耳后) LM Granulomatous inflammatory reactions Fibrosis，absence of nerves
UNIV Taberauloilesnady Clinical pathologic conference Anesthesias atrophy, contractures, paral ysis. liable to trauma, autoamputation of fingers or toes
Tuberculoid leprosy Clinical pathologic conference Anesthesias, atrophy, contractures, paralysis, liable to trauma, autoamputation of fingers or toes
UNIV 多wyB2B2 energie immunity lepromin test(-) Large amouts of bacilli infectious Acute deteriorate, poor prognosis Generally involved the skin, peripheral nerves anterior eye, upper airways, testes, lymph node, viscera
Lepromatous leprosy (20%) anergic immunity lepromin test (-) Large amouts of bacilli infectious Acute deteriorate, poor prognosis Generally involved the skin, peripheral nerves, anterior eye, upper airways, testes, lymph node, viscera
UNIV JX large aggregates of lipid laden macrophages(lepra cells), often filled with masses of acid-fast bacill Lack CD4+ THI cells at the margins but instead contain many CD8+ suppressor Tcells
Lepromatous leprosy large aggregates of lipid laden macrophages (lepra cells), often filled with masses of acid-fast bacilli Lack CD4+ TH1 cells at the margins but instead contain many CD8+ suppressor T cells
UNIV Skin lesions mAcular, papular, or nodular lesions form on the face. ears. back. extremites leonine faces hypoesthetic or anesthetic
Lepromatous leprosy Skin lesions: Macular, papular, or nodular lesions form on the face, ears, back, extremites leonine faces hypoesthetic or anesthetic