Selected syntheses by the Corey Group(1961~99) 1974 a《y Bceeau-a 84197801 其.r 1975184 +于m (-bowancie esr 2 CCO,H 1981y=0I 一 r.r. G-h-gafestol 98-30 y oirodowanin 1829/941 enin gogic giycinoeokepin A 418s057 exotoxin grsp tnonDounne t2《ts2
Selected syntheses by the Corey Group (1961~99)
EJ.Corey的合成工作 *(1)大环结构,如红霉素大环内酯; *(2)杂环结构如翼萼藤碱; *(3)倍半萜类化合物如长叶烯; *(4)多环异戊二烯类化合物如银杏内酯; *(5)前列腺类化合物,如前列腺素E1; *(6)白三烯类化合物,如白三烯A等; *(7)美登木素及其衍生物
E.J.Corey的合成工作 (1) 大环结构，如红霉素大环内酯； (2) 杂环结构如翼萼藤碱； (3) 倍半萜类化合物如长叶烯； (4) 多环异戊二烯类化合物如银杏内酯； (5) 前列腺类化合物，如前列腺素E1； (6) 白三烯类化合物，如白三烯A等； (7) 美登木素及其衍生物
科里(E| as James Corey) *从2050s后期开始有机合成研究,多年来与其同 事们共同合成了几百个重要天然化合物,结构比 较复杂,合成难度很大; *1967年提出了具有严格逻辑性的“逆合成分析原 理”,及合成过程中的有关原则和方法。按照他 的原理,使很多合成难度较大的有机化合物,得 到较高收率而获成功; *按照科里和其学生在1989年出版的专著《化学合 成的逻辑》一书的分类,科里不仅在有机合成研 究方面显示出天才,还总结出重要理论
科里(Elias James Corey) 从20’50s后期开始有机合成研究，多年来与其同 事们共同合成了几百个重要天然化合物，结构比 较复杂，合成难度很大； 1967年提出了具有严格逻辑性的“逆合成分析原 理”，及合成过程中的有关原则和方法。按照他 的原理，使很多合成难度较大的有机化合物，得 到较高收率而获成功； 按照科里和其学生在1989年出版的专著《化学合 成的逻辑》一书的分类，科里不仅在有机合成研 究方面显示出天才，还总结出重要理论
E.J. Corey Important concepts Synthon Retrosynthesis Retrosynthesis Analysis k 1990 Nobel prize
E. J. Corey Important concepts Synthon Retrosynthesis Retrosynthesis Analysis 1990 Nobel Prize
What E.J. Corey said about the Synthesis of Modern Drugs The discovery of efficacious new human therapeutic agents is one of humanity' s most vital tasks. It is an enormously demanding activity that requires creativit y, a vast range of scientific C knowledge, and great persistence. It is also an exceedingly expensive activity. In an ideal world, no education would be complete without some exposure to the ways in which new medicines are discovered and developed. For those young people interested in science or medicine, such knowledge is arguably mandatory
What E.J. Corey said about the Synthesis of Modern Drugs The discover y of efficacious new human therapeutic agents is one of humanity’s most vital tasks. It is an enormously demanding activity that requires creativity, a vast range of scientific knowledge, and great persistence. It is also an exceedingly expensive activity. In an ideal world, no education would be complete without some exposure to the ways in which new medicines are discovered and developed. For those young people interested in science or medicine, such k n o w l e d g e i s a r g u a b l y m a n d a t o r y