Features Clinical feature: endotoxemia and shock young baby is easy to suffer from sepsis, and deteriorate to MODS. it can be asymptomatic Blood test: WBC elevates or drops Metastatic foci: more commonly
Clinical feature： endotoxemia and shock young baby is easy to suffer from sepsis, and deteriorate to MODS.it can be asymptomatic Blood test：WBC elavates or drops Metastatic foci：more commonly Features
classification Shock virulence fever feature or MOSF DIO Common pathogens High common pneumococcus, fever common no E coli) Pathogens with High strong v acute (staphylococcus fever Severely ill more more aureus, pseudomonas, to drop klebsiella) Conditional athogens low subacute (staphylococcus medium common epidermidis
virulence fever feature Shock or DIC MOSF common Common pathogens （pneumococcus, E.coli） High fever common no no acute Pathogens with strong v （staphylococcus aureus,pseudomonas, klebsiella） High fever to drop Severely ill more more subacute Conditional pathogens （staphylococcus epidermidis） low ～ medium common no no classification
Mechanism Gram-negative Gram-positive bacteria bacteria lipoteichoic acid Endotoxin peptIdogly complex Comp l ement system coagulation cascades endothe Adrenocorticotrophic hormone Immno cell kallikrein-kinin system ACTH, RAS InfAmmatory mediators SIRS MOSF
Mechanism Gram-negative bacteria Gram-positive bacteria Endotoxin Lipoteichoic acid -peptidoglycan complex SIRS Inflmmatory mediators ACTH,RAS endothe Immno cell Complement system、 coagulation cascades Adrenocorticotrophic hormone kallikrein-kinin system MOSF
Complication Metastatic foci endocarditis, meningitis, oestoarthritis, and so on mulnutrition Disturbed hemostasis: such as acidosis Complications in organs dysfunction
Metastatic foci： endocarditis,meningitis,oestoarthritis,and so on mulnutrition Disturbed hemostasis：such as acidosis Complications in organs:dysfunction Complication