Pathology ◆ Proliferation of squamous epithilium ◆ Extension of papillary ◆ metaplasia www.zshospital.com
www.zshospital.com Pathology Proliferation of squamous epithilium Extension of papillary Metaplasia
@: Manifestation of GERD Typical symptoms of reflux Heartburn, regurgitation Irritation of reflux to esophagus Chest pain(nccp), dysphagia, Odynophagia, etc. Extra-esophageal symptoms Cough, Pharyngitis, asthma, bolus, etc. www.zshospital.com
www.zshospital.com Typical symptoms of reflux Heartburn, regurgitation Irritation of reflux to esophagus Chest pain(NCCP), dysphagia, Odynophagia, etc. Extra-esophageal symptoms Cough, Pharyngitis, asthma, bolus, etc. Manifestation of GERD
GERD is a condition which develops when the reflux of gastric content causes troublesome symptoms or complications Esophageal Syndromes Extraesophageal Syndromes Symptomatic Syndromes with Established Proposed S yndromes Es sophageal InJury Associations Associations 1. Pharyngitis 1. Typical Reflux 1. Reflux Esophagitis 2. Sinusitis Syndrome 2. Reflux Stricture 1. Reflux Cough Syndrome 3. Idiopathic 3. Barrett's Esophag 2. Reflux Laryngitis Syndrome ulmonary 2. Reflux Chest 4. Esophageal 3. Reflux Asthma Syndrome 4. Reflux Dental Erosion Fibrosis Pain Adenocarcinoma 4. Recurrent Otitis Syndrome Syndrome Media The Montreal Definition and Classification of Gastroesophageal Reflux Disease Am J Gastroenterol 2006: 101: 1900-1920 www.zshospital.com
www.zshospital.com The Montreal Definition and Classification of Gastroesophageal Reflux Disease Am J Gastroenterol 2006;101:1900–1920
Manifestation of gerd Complications upper gastrointestinal bleeding esophageal stricture carcinoma Notes: 1. symptoms severity 2. 2/3 regurgitation without symptoms Www.zsnospltal.com
www.zshospital.com • Complications upper gastrointestinal bleeding esophageal stricture carcinoma Manifestation of GERD Notes:1. symptoms～severity 2. 2/3 regurgitation without symptoms ×
复旦大学附属中山医院 Zhongshan Hospital, Fudan University Diagnostic approachs www.zshospital.com
www.zshospital.com Diagnostic approachs