Spindle Spindle(纺锤体)：The cellular spindle apparatus includes the spindle microtubules,associated proteins, with centrosomes or asters present at the spindle poles. It plays an important role in cell division and chromosome separation. ●Polar microtubule(连续微管)：Linking2 centrosomes, not continuous MT. ●Kinetochore microtubule(动粒微管)：Linking centrosome and centromere. ●Aster microtubule(星体微管)：Microtubules surrounding the centrosome and have a free end. 11 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
The three types of spindle microtubules spindle pole replicated chromosome kinetochore centrosome (sister chromatids) motor 十工夏 + protein astral microtubules kinetochore microtubules interpolar microtubules This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
(4)Anaphase (anaphase A and anaphase B) Sister chromatids split and migrate to opposite poles of the cell-separation of centromere. Pulling by the Kinetochore microtubules(Anaphase A) Growth and mutual sliding of the polar microtubules (Anaphase B) This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more informatior
ANAPHASE A shortening of kinetochore microtubules;movement of daughter chromosomes to poles;forces generated mainly at kinetochores This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
ANAPHASE B 1 (1)a sliding force is generated between interpolar microtubules from opposite poles to push the poles apart;the interpolar microtubules also elongate; (2)a pulling force acts directly on the poles to move them apart microtubule growth at plus end of polar microtubules This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information