第一节核被膜第二节染色质第三节染色质的复制与表达第四节染色体第五节核仁与核体第六节核基质
第一节 核被膜 第二节 染色质 第三节 染色质的复制与表达 第四节 染色体 第五节 核仁与核体 第六节 核基质
第一节核被膜(nuclearenvelope)OutermembraneInnermembrane核膜SmoothPerinuclearendoplasmicspace核孔复合体reticulum三、核纤层ChromatinNuclearRibosomeslaminaRoughNuclearendoplasmicNucleolusporecomplexreticulumhttp://faculty.samford.edu/~djohnso2/44962/405/nucleus.htmlTHECELL, FourthEdifion,Figure9.1 (Part3)G:2006ASMPrets andSinauerAssociates,inc
第一节 核被膜（nuclear envelope） 一、核膜 二、核孔复合体 三、核纤层
一、核膜NUCLEOPLASMInnermembraneNuclearof nuclear envelope（一）核膜结构pore complex+120nm→"Basket"CytoplasmAnchoroffibers.proteinNuclearPeripheral ERRinglaminasubunitH外层核被膜内层核被膜Outer0ONM核周间隙membraneNPCNPCofnuclearTransporterNMenvelope8AFiberNuclearlaminaEndoplasmicNucleoplasmreticulumRibosomesCYTOSOL(b) Locationof nuclearpores in nuclearmembranee2012PearsonEducafio, Inc
（一）核膜结构 外层核被膜 内层核被膜 核周间隙 一、核膜
（二）核膜的崩解与组装nuclearporelaminsDNAcomplexinnernuclearmembranenuclearnuclearenvelopeouternuclearmembranePHOSPHORYLATIONporeOFLAMINScomplexFUSIONOFENVELOPEDphosphorylatedproteinsCHROMOSOMESlaminsINTERPHASENUCLEUSchromatidnuclearchromosomeenvelopeLATEfragmentTELOPHASEPROPHASEDEPHOSPHORYLATIONFUSIONOFNUCLEAROFLAMINSENVELOPEFRAGMENTSEARLYTELOPHASEBreakdownandreformationofnuclearenvelopeduringmitosis
Breakdown and reformation of nuclear envelope during mitosis （二）核膜的崩解与组装
二、核孔复合体(NPC)TheNuclearPoreComplexCell ScienceS.Bagley,MW.Goldberg,J.M.Cronshaw, S.A.Rutherford and T.D.Allenyt
二、核孔复合体（NPC）