50 million individuals in the USA Approximately 1 billion individuals worldwide. As the population ages,the prevalence of hypertension will increase even further unless broad and effective preventive measures are implemented. 11
11 50 million individuals in the USA Approximately 1 billion individuals worldwide. As the population ages, the prevalence of hypertension will increase even further unless broad and effective preventive measures are implemented
Incidence of hypertension SBP≥140mmHg (%) DBP>≥90mmHg 90 males females 000000000 35-44 45-54 55-64 65-74 ≥75 12
12 Incidence of hypertension 10 20 30 40 50 60 70 35-44 45-54 55-64 65-74 ≥75 SBP≥140mmHg DBP≥90mmHg 80 90 males females (%) 0
Epidemiology 1n1999-2000 70%are aware of their HTN 59%are getting treatment 34%are controlled at target BPs from JNC 7 14
14 Epidemiology ▪ In 1999-2000 70% are aware of their HTN 59% are getting treatment 34% are controlled at target BPs from JNC 7
3.Causes of EH No single or specific cause is known. The interaction between genes and environment leads to hypertension (1)Genetic factors: 15
15 3. Causes of EH ▪ No single or specific cause is known. ▪ The interaction between genes and environment leads to hypertension ⑴ Genetic factors:
3.Causes of EH (1)Genetic Predisposition-Genetic alternations may initiate the cascade to permanent hypertension.Approximately 30% of cases of essential hypertension are attributable to genetic factors. 16
16 3. Causes of EH ⑴ Genetic Predisposition-Genetic alternations may initiate the cascade to permanent hypertension. Approximately 30 % of cases of essential hypertension are attributable to genetic factors