Physical properties of fatty acids 1) Determined by length and degree of unsaturation of hydrocarbon chain 2)Melting points 3) Solubility in water and benzene
Physical Properties of Fatty Acids 1) Determined by length and degree of unsaturation of hydrocarbon chain. 2) Melting points 3) Solubility in water and benzene
Structural Basis of Melting points for fatty acids Some Naturally Occurring Fatty Acids solubility at30°c on name Melting Structure Systematic point (C) Water Benzene CH3(CH2)IoCOOH n-Dodecanoi 442 0632,600 CH3(CH2)12CO0H n-Tetradecanoic acid Myristic acid 5390.024874 (Latin Myristica meg f 16:0 CH:(CH2)14CO0H n-Hexadecanoic acid ic acid 6310.0083348 tin palma, Im tree") 18:0 CH,(CH,)1 COOH n-Octadecanoic acid 69.60.003412 Greek stear 20:0 CHa(CH2)1BCOOH n-Eicosanoic acid acidic ac 76.5 (Latin Arachis legume ge 24:0 C 86.0 wood"+cera,“wax" 16:1(△) CH3(CH2)s CH-CH(CH2)7C00H cis-9-Hexadecenoic acid Palmitoleic acid 0.5 18:1(A%) CH3(CH2))CH-CH(CH2)COOH cis-9-Octadecenoic acid ( Lat 13.4 n oleum 18: 2(492)CH3(CH2)4CH=, CH= cis, cis-9, 12-0ctadecadienoic Linoleic acid 5 CH(CH2)CO0H ( Greek /inon,“fax") 18:3(49.12. 15)CH3CH2CH-CHCH2CH= a-Linolenic acid 11 CHCH2CH-CH(CH2)7CO0H Octadecatrienoic acid 20:4(△58114cH3CH )ACH=CHCH2 CH cis, Cis, cis, cis-5, 8, 11, 14- Arachidonic acid -49.5 CHCH Icosatetraenoic acid CH(CH2)3COOH All acids are shown in their nonionized form. At pH 7, all free fatty acids have an ionized carboxy late. Note that numbering of carbon atoms begins at the i carbon TThe prefix n- indicate normal"unbranched structure. For instance, dodecanoic"simply indicates 12 carbon atoms, which could be arranged in a varie configuration of each bond is indicated; in biological fatty acids the configuration is almost always cis
Structural Basis of Melting points for fatty acids
Biologically speaking In vertebrates, free fatty acids (unesterified fatty acids having a free carboxylate group circulate in the blood bound noncovalently to a protein carrier, serum albumin However, most of the fatty acids are derivatives of esters or amides--thus lack the charged carboxylate group- less soluble
In vertebrates, free fatty acids (unesterified fatty acids having a free carboxylate group) circulate in the blood bound noncovalently to a protein carrier, serum albumin. However, most of the fatty acids are derivatives of esters or amides—thus, lack the charged carboxylate group— less soluble. Biologically speaking…
diacylglycerols -fatty acid ester of glycerol also called triglycerides, fats or neutral fats csimple triacylglycerolsall three fatty acids are the same eg,16: 0-tristearin; 18: 0-tripalmitin, 18: 1 triolein mixed triacylglycerol-two or more fatty acids triacylglycerols are nonpolar, hydrophobic and insoluble (oil/water--never mix)
Triacylglycerols —fatty acid ester of glycerol also called triglycerides, fats or neutral fats --simple triacylglycerols—all three fatty acids are the same, e.g., 16:0-tristearin; 18:0-tripalmitin, 18:1- triolein --mixed triacylglycerol-two or more fatty acids -- triacylglycerols are nonpolar, hydrophobic and insoluble (oil/water—never mix)
H. Ch 1-stearoyl, 2-linoleoyl, 3- OH palmitoyl glycerol Glycerol A mixed triglyceride C2 is a chiral center 1-Stearoyl, 2-linoleoyl, 3-palmitoyl glycerol a mixed triacylglycerol
1-stearoyl, 2-linoleoyl,3- palmitoyl glycerol A mixed triglyceride C2 is a chiral center