But!Wred eye (w.t)Win Drosophilawhite eye (mut)WaAmygdaloideye(mut)Xw-XwaX Xw-XwXw-YWXw-Xw-1/1000XwaW.tXw-XwaXwaYred eye
But ! W w - wa red eye (w.t) Xw- Xwa × Xw-Y Xw- Y Xw- Xw- Xw- Xw-Y Xwa Xw- Xwa XwaY ? 1/1000 W.t red eye white eye (mut) Amygdaloid eye (mut) in Drosophila
Pseudo Alleles紧密连锁（交换率极低）功能相同（表型相似，缺一不可）A1a2A2A1w.t.A2a2alamut
紧密连锁 （交换率极低） 功能相同 （表型相似，缺一不可） Pseudo Alleles A1 A2 a1 a2 w.t. mut. A1 a2 a1 A2
Theory of cistron (S.Benzer 1955)3o0t-7h13ise
Theory of cistron (S.Benzer 1955)
T4 PhageMut. rII : rII107, rII105, rII51, rI147......(400)plaquePhageE.coli BE.coli k12白，小，边缘模糊W.t T4白，小，边缘模糊Mut.T4 rII大，园，边缘清晰
T4 Phage Mut. rII : rII107, rII105, rII51, rII47.(400) Phage E.coli B E.coli k12 plaque W.t T4 Mut.T4 rII 白, 小, 边缘模糊 白, 小, 边缘模糊 大, 园, 边缘清晰 ！
Recombination assayO...rl147O.福X-rll102Blotting intoplaneplaneE.coliBE.coliK12r1147.?CCrll104OH
plane E.coli B Blotting into plane E.coli K12 Recombination assay E.coli B rII47 0 0 rII102 0 0 rII47 rII104