2) Role of Th cells in humoral immune response to TD-Ag For a protein Ag to stimulate Ab response, b cells and th cells specific for that Ag must come together in lymphoid organs and interact in a way that stimulates B cell proliferation and differentiation
2) Role of Th cells in humoral immune response to TD-Ag For a protein Ag to stimulate Ab response, B cells and Th cells specific for that Ag must come together in lymphoid organs and interact in a way that stimulates B cell proliferation and differentiation
a Activation and migration of helper t cells o Th cells that have been activated to differentiate into effector cellis interact with antigen-stimulated B cells at the edges of lymphoid follicles in the peripheral lymphoid organs
a. Activation and migration of helper T cells Th cells that have been activated to differentiate into effector cells interact with antigen-stimulated B cells at the edges of lymphoid follicles in the peripheral lymphoid organs
Antigen presentation Antigen recognition and T cell activation by b cells Parafollicular Lymphoid Microbe Microbe cortex(T cell follicle Naive CD4 zone) (B cell B Lymph: T cell zone) B cell node activation APC T cell proliferation and differentiation Migration Effector CD4 T: B cel H/+ Mig gration T cells interactions OElsevierAbbas&LichtmanBasicImmunologyUpdated2e-www.studentconsult.com The interactions of Th cells and b cells in lymphoid tissues
The interactions of Th cells and B cells in lymphoid tissues