COURSE OF BRUCELLOSIS If the disease is not treated, the symptoms may continue for 2 to 4 weeks Many patients will then recover spontaneously Others may suffer a series of exacerbations May produce an undulant fever in which the intensity of fever and symptoms recur and recede at about 10 day intervals
COURSE OF BRUCELLOSIS • If the disease is not treated, the symptoms may continue for 2 to 4 weeks – Many patients will then recover spontaneously – Others may suffer a series of exacerbations • May produce an undulant fever in which the intensity of fever and symptoms recur and recede at about 10 day intervals
Brucellosis Cyprus fever/Gibraltar fever/Malta fever/ rock fever/undulant fever Most affected persons recover entirely within Undulant fever 3 to 12 months Some will develop complications involvement of various organs a few may enter an ill-defined chronIc syndrome
Brucellosis • Cyprus fever/Gibraltar fever/Malta fever/Rock fever/Undulant fever Undulant fever 39.5 37.0 • Most affected persons recover entirely within 3 to 12 months • Some will develop complications – involvement of various organs, – a few may enter an ill-defined chronic syndrome
COMPLICATIONS Arthritis, often sacroiliitis, and spondylitis (in about 10 percent of cases) central nervous system involvement including meningitis (in about 5%) Uveitis, epididymo-orchitis Endocarditis very rare In contrast to animals. a bortion is not a feature of brucellosis in pregnant women
COMPLICATIONS • Arthritis, often sacroiliitis, and spondylitis (in about 10 percent of cases) • central nervous system involvement including meningitis (in about 5%) • Uveitis, epididymo-orchitis • Endocarditis very rare • In contrast to animals, abortion is not a feature of brucellosis in pregnant women
LARGE JOINTS Slice 10/20 vastus lateralis n Vastus medialis m ateral femoral condyle Medial femoral condyle Fibular collateral ligament Posterior cruciate ligament Anterior cruciate ligament Tibial collateral ligament Lateral meniscus niscus Condylar articular cartilage Intercondylar eminence Lateral tibial condyle Medial tibial condyle Pes anserinus Extensor digitorum longus m Tibialis posterior m
LARGE JOINTS
SPONDYLITIS脊椎炎 Slice 7/13 Diaphragm(crus) Kidney L2-L3 intervertebral disc Lumbar a and y Retroperitoneal fal L5 vertebral body Common iliac v Common iliac a Common iliac y Internal iliac a External iliac a
SPONDYLITIS脊椎炎