Medical Genetics The segments retained in the mRNA they called exons and the intervening sequences(A, B and C), which are excised during mRNA processing and maturation, are called introns hybridization poly A-tail messenger RNA c B DNA mRNA w
Medical Genetics The segments retained in the mRNA they called exons and the intervening sequences (A, B and C), which are excised during mRNA processing and maturation, are called introns
Medical Genetics DNA-RNA nyora
Medical Genetics
Medical Genetics GENES RNA, AND PROTEINS: FROM SIMPLICITY TO COMPLEXITY transcription translation GENES RNA PROTEINS MODIFIED PROTEINS DNA co-and post-trans latiional 2. prenylation coding sequence 3. glycosylation 4. phosphorylation DNA regulator primary transcript Introns splicing mRNA
Medical Genetics
Medical Genetics ATP7A in Menke disease Upstream BRCA1 in Enhancers Breast Cancer Exonic Splicing GT Splice Silencer(ESS) Donor Transcription Factor Binding Site Exonic Splicing INTRON INTRON Enhancer (ESE) EXON EXON3'UTR Intronic Splicing Upstream TATA Enhancer(ISE) Intronic Splicing repressors Silencer(ISS) Poly A signal CYP2D6 Alpha galactosidase AG Splice Acceptor Fabry Disease in FOXP3 in TSS IPEX syndrome Promoter Region
Medical Genetics
Medical Genetics Membrane traffic protein Lyase Transfer /carrier proteln Synthase and synthetase Isomerase Extracellular matrix Chaperone Select calcium binding protein Ce‖ nction prolIn sphatase Defnse/immunity protein Reoeplr Cell adhesin molecule Transfer Cymose latal protein Transporter一 Molecular function undassifed Miscellaneous function lon chan nel- Hydron Nudelc ack binding Protease KInase selct regulatory molecule Transcription fact ignaling m
Medical Genetics