Chronic hepatitis (CH) 14 2 Peretratrg we Hepatic stellate cell (HsC) Hepatic limiting plane??(interface of stroma and hepatocytes surrounding hepatic lobules) Interface hepatitis hepatocytes of limiting plane happen necrosis Piecemeal necrosis: hepatic limiting plane breakdown
Chronic hepatitis （CH） Hepatic limiting plane?? (interface of stroma and hepatocytes surrounding hepatic lobules) Hepatic stellate cell (HSC) Interface hepatitis: hepatocytes of limiting plane happen necrosis. Piecemeal necrosis: hepatic limiting plane breakdown 14
15 Chronic hepatitis(Ch) (there are three points need to pay attention) CH course: at least 6 months Appears: symptomatic, biochemical, or serologic evidence of hepatic diseases for more than 6 months shows histologically documented inflammation and necrosIs cause: hepatitis viruses are responsible for most cases, other many factors(no study Wilson disease alcoholic, drugs and autoimmunity(Alh Pbc)
Chronic hepatitis (CH ) CH ------ course: at least 6 months. Appears: symptomatic, biochemical, or serologic evidence of hepatic diseases for more than 6 months, -----shows histologically documented inflammation and necrosis. ----- cause: hepatitis viruses are responsible for most cases, other many factors (no study) Wilson disease, alcoholic, drugs and autoimmunity (AIH、PBC) (there are three points need to pay attention) 15