1. Locus ceruleus-norepinephrine /sympathetic-adrenal meddula axis, LC/NE (1)Central site ofLC/Ne Limbic system: emotion/cognition/action Lateral horn of spinal cord: sympathetic adrenal meddula CALA)
1.Locus ceruleus-norepinephrine /sympathetic-adrenal meddula axis, LC/NE (1)Central site of LC/NE Limbic system: emotion/cognition/action Lateral horn of spinal cord: sympatheticadrenal meddula
(2Effects of catecholamine during stress Central: exiting, alert/tension, anxiety Peripheral: / Locus ceruleus arouses the brain Sympathetics activate entire body
(2)Effects of catecholamine during stress Central: exiting , alert / tension, anxiety Peripheral: ?/? Locus Ceruleus arouses the Brain Sympathetics activate entire body
1)Peripheral beneficial effects (cArdiovascular function hypermetabolism: glycogenolysis respiration promoting secretion of other hormone ⑤ hyperglycemia
1)Peripheral beneficial effects : ①Cardiovascular function ②hypermetabolism: glycogenolysis ③respiration ④promoting secretion of other hormone ⑤hyperglycemia
2)Peripheral detrimental effects: Hypertension ischemia ② thrombosis 30, overconsumption: HR ④ lipid peroxidation Adr、 Methyl transferase Ⅴ vanillylmandelic monoamine oxidase acid (VMA) 80%during stress O2…·个 adrenochrol
2)Peripheral detrimental effects : ①hypertension & ischemia ②thrombosis ③O2 overconsumption: HR ④lipid peroxidation Adr Methyl transferase monoamine oxidase Vanillylmandelic acid (VMA) 80% during stress O2 adrenochrome -·
Parasympathetic SAM-Route Sympathetic s Dilates Stimulates In hibits floy floy of saliva Ganglion of saliva dulla oblongata→ SI Accelerates heartbeat heartbeat agu nerye Constricts Eilat es bronc hi bronc hi Solar exUS Stim ulates Inhibits peristalsis peristalsis and secretion and secretion Conversion Stimulate of glyc to glucose release of bile Secretion of adrenaline and noradrenaline Contracts Inhibits Ean 0 bladder bladder sympathetic contraction ganglia Rest and digest? Stress “ Fight or Flight
SAM-Route “ Stress Rest and Digest” “Fight or Flight