mRNAis localized at anterior end 29.5 Anterior development uses localized gene regulators mRNA is trans lated Figure 29.5 Translation △V△ of a localized mRNA generates a gradient of protein as the products Protein diffuses from site of synthesis diffuses away from the site of synthesis. 情華大当
Figure 29.5 Translation of a localized mRNA generates a gradient of protein as the products diffuses away from the site of synthesis. 29.5 Anterior development uses localized gene regulators
29.5 Anterior development uses localized gene regulators Donor Wild-type embryo Figure 29.6 Mutant embryos that cannot develop can be rescued by injecting cytoplasm taken from a wild-type embryo.The donor can be tested for time of appearance and Remove material from donor location of the rescuing activity;the and microinject into recipient recipient can be tested for time at which it is susceptible to rescue and the effects of injecting material at Recipient different locations. Mutant embryo 清第大当
Figure 29.6 Mutant embryos that cannot develop can be rescued by injecting cytoplasm taken from a wild-type embryo. The donor can be tested for time of appearance and location of the rescuing activity; the recipient can be tested for time at which it is susceptible to rescue and the effects of injecting material at different locations. 29.5 Anterior development uses localized gene regulators
29.5 Anterior Protein staining development uses 100 localized gene regulators 75 Figure 29.7 Bicoid protein 50 forms a gradient during D. melanogaster development 25 that extends for ~200 mm along the egg of 500 mm. mm100 200 300 400 500 anterior posterior 清菜大当
Figure 29.7 Bicoid protein forms a gradient during D. melanogaster development that extends for ~200 mm along the egg of 500 mm. 29.5 Anterior development uses localized gene regulators
29.5 Anterior Protein staining development uses 100 localized gene regulators 75 Figure 29.7 Bicoid protein 50 forms a gradient during D melanogaster development 25 that extends for ~200 mm along the egg of 500 mm. mm100 200 300 400 500 anterior posterior 清菜大当
Figure 29.7 Bicoid protein forms a gradient during D. melanogaster development that extends for ~200 mm along the egg of 500 mm. 29.5 Anterior development uses localized gene regulators
29.5 Anterior development uses localized gene regulators Anterior system Posterior system Dorsal-vertral system bicoRNAis anterior Toll protein is ubiqiuitous Egg spaize protein(and therefore Toll)is activated Produdts ventrally transported oractivated by nurse or Toll protein follide cells bicoid protein forms gradiert nanos protein dorsal proteinis cytoplasmic Svncvtial is inpo 990080e合600 Maternal RNAs are translated RQQRROBSBBSSORO nudear dorsa protein on ventral side hunchback RNA fills arterior region 支ripes of初s&gFNA dpp&zen RNA are dorsal Cellular Zyootic knipsgia RNAs a nscribed 3色5pF5平 twist snai/RNA are ventra Figure 29.17 In each axis-determining system,localized products in the egg cause other maternal RNAs or proteins to be broadly localized at syncytial blastoderm,and zygotic RNAs are transcribed in bands at cellular blastoderm. 清菜大当
Figure 29.17 In each axis-determining system, localized products in the egg cause other maternal RNAs or proteins to be broadly localized at syncytial blastoderm, and zygotic RNAs are transcribed in bands at cellular blastoderm. 29.5 Anterior development uses localized gene regulators