ORGANIC CHEMISTRY Chapter ll 11. 8 Reactions of alcohols Nucleophile Nucleophilic substitution C-0 H H Oxidation Acidity Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 11 11.8 Reactions of Alcohols C H O H δ+ δ δ+ Nucleophile Nucleophilic substitution Oxidation Acidity
ORGANIC CHEMISTRY Chapter ll Unstable Alcohols CH -CH-OH Ch c-H OH CHrch CH3 C-H +H,O OH CH3-C-CH3 CH3C-CH3 H2O OH OH CH3CH CH3C-H +hc CI Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 11 Unstable Alcohols CH2 CH OH CH3C O H CH3CH OH OH CH3C O H C OH OH CH3 CH3 C O CH3 CH3 CH3CH OH Cl CH3C O H + H2O + H2O + HCl
ORGANIC CHEMISTRY Chapter ll 11 9 Alcohols as acids Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 11 11.9 Alcohols as Acids
ORGANIC CHEMISTRY Chapter ll Compounds (CH3)3 COH 18.00 CHrCH,OH 16.00 HOH 15.74 ChOH 15.54 CF3 CHOH 12.43 (CF3) COH 54 HCl 7.00 Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 11 18.00 16.00 15.74 15.54 12.43 5.4 7.00 Compounds pKa (CH3)3COH CH3CH2OH HOH CH3OH CF3CH2OH (CF3)3COH HCl
ORGANIC CHEMISTRY Chapter ll ROH Na RONa +h Reactivity Ch3oH> CH3,OH> CH3 CH,CH,OH> CH3)2CHOH >(CH3)3COH CH3 CH,ONa H,O ch choo naoh Department of Chemistry, Xiamen University
ORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 11 + Na RONa + H2 Reactivity CH3OH > CH3CH2OH > CH3CH2CH2OH > (CH3)2CHOH > (CH3)3COH ROH CH3CH2ONa + H2O CH3CH2OH + NaOH