H iymphocytes ACu作 E RHEUMATIG HEART OISEASE CROSS-REACTIONS Myocardial Ascher body Fennous percaroitn Pathogenesis and key morphologic changes of acute rheumatic heart disease
Pathogenesis and key morphologic changes of acute rheumatic heart disease
Basic pathologic changes 3 stages Degeneration Exudation fibrinoid necrosis, inflammtory infiltrates Regeneration rheumatic granuloma (rheumatic body, Aschoff body) Sclerosis fibrosis, scarring
Basic pathologic changes 3 stages ◼ Degeneration & Exudation fibrinoid necrosis, inflammtory infiltrates ◼ Regeneration rheumatic granuloma (rheumatic body, Aschoff body) ◼ Sclerosis fibrosis, scarring
Rheumatic Heart Disease (RHD) Acute(Pancarditis In rheumatic fever, any layer of the heart can be involved, including endocarditis, myocarditis and pericarditis. All three basic changes can be observed Chronic Characterized by repeated inflammation with fibrinous resolution, result in severe anatomic change of valves, include leaflet thickening, commissural fusion and shortening and thickening of the tendinous cords
Rheumatic Heart Disease (RHD) ◼ Acute (Pancarditis) In rheumatic fever, any layer of the heart can be involved, including endocarditis, myocarditis and pericarditis. All three basic changes can be observed. ◼ Chronic Characterized by repeated inflammation with fibrinous resolution, result in severe anatomic change of valves, include leaflet thickening, commissural fusion and shortening and thickening of the tendinous cords
Acute RHD Rheumatic pericarditis cor villosum: fibrinous pericarditis, associated with a serous pericardial effusion
Acute RHD Rheumatic pericarditis cor villosum: fibrinous pericarditis, associated with a serous pericardial effusion
