lateral diffusion 袭终测 A flip-flop I(rarely I occurs flexion rotation B) fatty acid tails lipid head groups water molecules A) Figure 10-11 Molecular Biology of the Cell(@ Garland Science 2008)
Figure 10-11 Molecular Biology of the Cell (© Garland Science 2008)
00 unsaturated saturated hydrocarbon chains ydrocarbon chains with cis-double bonds Figure 10-12 Molecular Biology of the Cell(@ Garland Science 2008)
Figure 10-12 Molecular Biology of the Cell (© Garland Science 2008)
The importance of the lipid bilayer The lipids of a membrane are more than simple structural elements It is a skeleton of the membrane ipid composition can determine the physical state of the membrane and influence the activity of particular membrane proteins Membrane lipids also provide the precursors for highly active chemical messengers that regulate cellular function
The importance of the lipid bilayer • The lipids of a membrane are more than simple structural elements: • It is a skeleton of the membrane • Lipid composition can determine the physical state of the membrane and influence the activity of particular membrane proteins. • Membrane lipids also provide the precursors for highly active chemical messengers that regulate cellular function
Q p bilayer (5 nm) lipid molecule protein molecule Figure 10-1c Molecular Biology of the Cell(@ Garland Science 2008)
Figure 10-1c Molecular Biology of the Cell (© Garland Science 2008)
(2) membrane protein accomplish a lot of important membrane functions 内在膜蛋白( intrinsic membrane protein) 整合膜蛋白( integral membrane protein) Membrane 外在膜蛋白( extrinsic membran e prote Proteins 外周蛋白( peripheral protein) 脂锚定蛋白( lipid anchored protein) 脂连接蛋白( lipid-linked protein)
（2）membrane protein accomplish a lot of important membrane functions Membrane Proteins 内在膜蛋白（intrinsic membrane protein） 整合膜蛋白（integral membrane protein） 外在膜蛋白(extrinsic membrane protein) 脂锚定蛋白（lipid anchored protein) 外周蛋白（peripheral protein） 脂连接蛋白（lipid-linked protein）