Intermembrane space pyruvate H 7 H 8 OH OH latrix
P404
3. The mitochondrial matrix Matrix has a gel-like consistency owing to the presence of a high concentration (up to 500 mg/ml) of water-soluble proteins, the mixture of hundreds of enzymes, including those required for the oxidation of pyruvate and fatty acids and for TCA cycle. Matrix also contains mtDNA genome, mt-ribosomes, and various enzymes required for expression of the mt-genes Filament and dense granules, one among which contain a store of calcium ions in the form of precipitates of calcium phosphate
3. The mitochondrial matrix Matrix has a gel-like consistency owing to the presence of a high concentration (up to 500 mg/ml ) of water-soluble proteins, the mixture of hundreds of enzymes, including those required for the oxidation of pyruvate and fatty acids and for TCA cycle. Matrix also contains mtDNA genome, mt-ribosomes, and various enzymes required for expression of the mt-genes. Filament and dense granules, one among which contain a store of calcium ions in the form of precipitates of calcium phosphate
器 ATP NADH H201/202+2H+ c02 Pi t ADP TCA cycle NADH C2 C6 ATP4- NADH NADH C3 Pyruvic acid nte space P
线粒体主要酶的分布 部位 酶 部 酶的 NADH细胞色素c还原酶(对/模间隙/腺苷酸激酶 外膜单胺氧化酶 二磷酸激酶 藤酮不敏感) 核苷酸激酶 犬尿酸羟化酶 酰基辅酶A合成酶 细胞色素b,c,c1a,a3氧化酶 柠檬酸合成酶、苹果酸脱氢酶 ATP合成酶系 延胡索酸酶、异柠檬酸脱氢酶 内膜|琥珀酸脱氢酶 基质顺乌头酸酶、谷氨酸脱氢酶 β-羟丁酸和β-羟丙酸脱氢酶 脂肪酸氧化酶系、 肉毒碱酰基转移酶 天冬氨酸转氨酶、 丙酮酸氧化酶 蛋白质和核酸合成酶系 NADH脱氢酶(对鱼藤酮敏感) 丙酮酸脱氢酶复合物
部位 酶 的 名 称 部 位 酶 的 名 称 外膜 单胺氧化酶 NADH-细胞色素c还原酶（对 鱼 藤酮不敏感） 犬尿酸羟化酶 酰基辅酶A合成酶 膜间隙 腺苷酸激酶 二磷酸激酶 核苷酸激酶 内膜 细胞色素b，c，c1，a，a3氧化酶 ATP合成酶系 琥珀酸脱氢酶 β-羟丁酸和β-羟丙酸脱氢酶 肉毒碱酰基转移酶 丙酮酸氧化酶 NADH脱氢酶（对鱼藤酮敏感） 基质 柠檬酸合成酶、苹果酸脱氢酶 延胡索酸酶、异柠檬酸脱氢酶 顺乌头酸酶、谷氨酸脱氢酶 脂肪酸氧化酶系、 天冬氨酸转氨酶、 蛋白质和核酸合成酶系、 丙酮酸脱氢酶复合物 线粒体主要酶的分布
12s D loop TRNA 16S rRNA C
P39 2-1