Abstract: Several 13-alkyl substituted analogs of berberine and palmatine were found to be highly active against two types of Staphylococcus aureus(SI and S2)of different origin. The most active 13-hexylberberine was 8 times more active(against SI)and the same order active(against
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Antibiotic drugs Among the hundreds of compounds produced by microorganisms that have inhibitory action on other microorganisms, only a relatively small number have a favorable therapeutic index. These are the clinically useful antibiotics. In the present discussion, particular attention will be paid to the potency, antibacterial spectrum
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Gonorrhoea What is gonorrhoea? Gonorrhoea is a yenereal disease caused by the bacteria Neisseria gonorrhoeae. The disease most frequently 15-25 affects 15-25-year-olds, although the number of cases has fallen in recent years. How do you contract gonorrhoea? Gonorrhoea is mainly transmitted through sexual contact. However, mothers infected with gonorrhoea can also
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How does it work? Ofloxacin belongs to a group of broad spectrum antibiotics called the quinolones. It works by entering the bacterial cell and inhibiting a chemical called DNA-gyrase which is involved in the production of genetic material (DNA). This therefore prevents the bacteria from reproducing
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性质 一、酸碱两性既含有酸性的酚羟基,又有碱性的叔氨基团 二、易被氧化成伪吗啡(双吗啡)和N-氧化吗啡 酸性条件下稳定,PH3-5
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先导化合物的发现 (Discovery of Lead compound) 新药开发的基本途径与方法 之 药物分子设计(Mo1ecu1a《drug design)是指通过科学的构思和理 性的策略,构建具有预期药理活性 的新化学实体(new《chemica1 entities)的分子操作
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药剂学是研究药物剂型及制剂的一门综合性学科 其主要研究内容包括:剂型的基础理论、制剂的生产 技术、产品的质量控制、合理的临床应用 研究、设计和开发药物新剂型及新制剂是其核心内容。 随着科学技术的飞速进步,特别是数理、生命、材料、电子和信息等科学领域的发展和信息等科学领域的发展和创造,极大地推动了药剂学的发展,使药剂学从经验探索阶段入了科学研究阶段
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中国药科大学:《药物化学》PPT教学课件_四环素类抗生素 Tetracycline Antibiotics、氨基糖甙类抗生素
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