Nephrotic Syndrome Department of Prdiatrics, Tongji Hospital Tel:83662684
Nephrotic Syndrome Department of Prdiatrics, Tongji Hospital Tel: 83662684
Nephrotic Syndrome Definition Etiology Pathology Pathophysiology Clinical manifestation Laboratory Data Diagnosis Therapy and prognosis
Nephrotic Syndrome • Definition • Etiology • Pathology • Pathophysiology • Clinical Manifestation • Laboratory Data • Diagnosis • Therapy and Prognosis
lale 4 years and 6 months old Complaint of edema and oliguria
Male 4 years and 6 months old Complaint of edema and oliguria
Definition: Nephrotic Criteria Massive proteinuria ISKDC:>40mg/m2/hr CAN: >++ trice/2w or >50-100mg/kg/24hr Mendoza: Urine Protein/Cr22.0 Hypoalbuminemia: 30g/L Hyperlipidemia: Cholesterol> 5.72mmol/L o Edema
Definition: Nephrotic Criteria • Massive proteinuria • ISKDC: > 40mg/m2 /hr • CAN: >+++ trice/2w or >50-100mg/kg/24hr • Mendoza: Urine Protein/Cr ≥2.0 • Hypoalbuminemia: < 30g/L • Hyperlipidemia:Cholesterol> 5.72mmol/L • Edema
Definition: Nephritic Criteria Hematuria: RBC+(>10/HP), trice/2w Hypertension: >130/90 mmHg in children over 7y >120/80 mm Hg in 3-6y children >110/70 mm Hg in 3y children Azotemia: bun>6. 4mmolL cr>133umolL Hypocomplementemia: C3<0.8/L
Definition: Nephritic Criteria • Hematuria: RBC ++( >10 /HP), trice/2w • Hypertension: • >130/90 mmHg in children over 7y • > 120/80 mm Hg in 3-6y children • > 110/70 mm Hg in < 3y children • Azotemia:BUN>6.4mmol/L, Cr >133umol/L • Hypocomplementemia: C3<0.8/L