1 1.4 acidity of alpha hydrogen Atoms: Enolate lon formation H pk2=58 H pK=36 0 B H pK2=19 00 00 pK2=9
11.4 Acidity of Alpha Hydrogen Atoms: Enolate Ion Formation H O O B - O - B - O O O O O O - O - O H pKa = 36 pKa = 58 H pKa = 9 pKa = 19
p351 Lithium Diisopropylamide (LDA) I(CH3)2CHI2NH+ Buli[(CH3)2CHINLi+ Buh LDA
Lithium Diisopropylamide (LDA) p.351 [(CH3 )2CH]2NH BuLi [(CH3 )2CH] + 2NLi +BuH LDA
11. 5 Reactivity of Enolate ions 人 OE 或
11.5 Reactivity of Enolate Ions O - O - E + E O OE 或
Halogenation of enolate lons The haloform(卤仿) Reaction B H HX ⅹX X/OH X OH R R0+hc R
Halogenation of Enolate Ions: The Haloform（卤仿） Reaction H O B O - X2 X O －HX X O X X R O X2 / OHR X O X X OHR O - [ ] R O - O + HCX3
11.6 Alkylation of Enolate Ions R'COCI RX O R 00 X: OTsL. Br. Cl R R:烯丙基,苄基,甲基,伯
11.6 Alkylation of Enolate Ions p.351 O R' O R'COCl X: OTs, I, Br, Cl R: 烯丙基， 苄基， 甲基， 伯 R RX O - O - O SN2