The transforming principle Harmless bacteria Mouse survives Harmless bacteria Mouse dies Virulent bacteria transforming principle Harmless bacteria Mouse dies Virulent bacteria transforming principle treated with protease or ribonuclease Harmless bacteria Mouse survives transforming principl treated with deoxyribonuclease
The Hershey-Chase DNA experiment Protein capsid-A Phage attached to bacteria Agitate in blender t Phage now o detached centrifuge a上 70%32p 20%355
1.1.2 The structure of dna (A)A nucleotide "0-Plo-PPo-P-o-cH2 BASE o 4'C Phosphate OH H Sugar (B)The four bases in DNA NH2 HN HC HC N C\3/CH N N NH2 O N Adenine(A) Cytosine(() Guanine (G) Thymine(T)
1.1.2 The structure of DNA
1.1.2 The structure of dna 5′- P terminus o-P-0-P-0-P-0一cH2 BASE 5 A phosphodiester bond 0=P-O-CH2 BASE 3 o=P一0-cH BASE OH 3-oH terminus
1.1.2 The structure of DNA
1.1.2 The structure of dna Table l1 features of different conformations of the dna double helix Feature B-DNA A-DNA Z-DNA Type of helⅸx Right-handed Right-handed Left-handed Helical diameter (nm) 2.37 2.55 1.84 Rise per base pair(nm) 0.34 0.29 Distance per complete turn(pitch)(nm) 3.4 3.2 4.5 Number of base pairs per complete turn Topology of major groove Wide, deep Narrow, deep Topology of minor groove Narrow, shallow Broad shallo Narrow. de
1.1.2 The structure of DNA