Definition Syphilis is a chronic sexually transmitted disease due to infection of Treponema pallidum, which may involve multiple systems, including skin and mucosa as well as cardiovascular system and neural system, and present with various clinical manifestations
Definition Syphilis is a chronic sexually transmitted disease due to infection of Treponema pallidum, which may involve multiple systems, including skin and mucosa as well as cardiovascular system and neural system, and present with various clinical manifestations
Etiology Syphilis is caused by infection of Treponema pallidum By dark-field microscopy, the characteristic motility of the pathogen can be observed, which consists of three movements a projection in the direction of the long axis a rotation on its long axis a twisting from side to side Treponema is not easy to survive in vitro. Boil, dry, soapsuds or common antiseptic can kill the pathogen
Etiology Syphilis is caused by infection of Treponema pallidum. By dark-field microscopy, the characteristic motility of the pathogen can be observed, which consists of three movements: – a projection in the direction of the long axis – a rotation on its long axis – a twisting from side to side. Treponema is not easy to survive in vitro. Boil, dry, soapsuds or common antiseptic can kill the pathogen
Transmission Epidemiology The primary mode of transmission: sexual contact The next most common is transfer across the placenta Blood transfusion Others: kissing, suckling, or contacting the blood, secretion, dunnage(clothes towel, razor, table dinner service, cigarette holder, etof the patients
Transmission & Epidemiology The primary mode of transmission: sexual contact. The next most common is transfer across the placenta . Blood transfusion. Others：kissing , suckling, or contacting the blood, secretion,dunnage (clothes, towel, razor, table dinner service, cigarette holder,et)of the patients
Course and stage of disease early syphilis(<2years): primary syphilis, secondary syphilis secondary syphilis(>2years) or tertiary syphilis tertiary cutaneous syphilis ,late osseous syphilis cardiovascular syphilis, neurosyphilis and others latent syphilis early latent syphilis (<2years late latent syphilis (>2years)
Course and stage of disease early syphilis（<2years）：primary syphilis, secondary syphilis secondary syphilis（>2years）or tertiary syphilis： tertiary cutaneous syphilis ,late osseous syphilis , cardiovascular syphilis,neurosyphilis and others latent syphilis ：early latent syphilis （<2years）, late latent syphilis （>2years）