Clinical manifestation Recurrent genital herpes It recurs for 5-8 times in the first year and less frequently in the years that follow Patients infected by hsv-1 less frequently suffer from recurrence than those by hsv-2 The duration may be 7 days The signs and symptoms of recurrent lesions are mild The recurrences of GH are triggered by trauma, fatigue, infection, menstrual or cold onset, and so on
Clinical manifestation Recurrent genital herpes – It recurs for 5~8 times in the first year and less frequently in the years that follow. – Patients infected by HSV-1 less frequently suffer from recurrence than those by HSV-2. – The duration may be 7 days. – The signs and symptoms of recurrent lesions are mild. – The recurrences of GH are triggered by trauma, fatigue, infection, menstrual or cold onset, and so on
hsv carcinomas cervicis Researches of recent years report that HSV-II is associated with the development of carcinoma cervicis, here are the evidences Women with GH correlate with a higher incidence of cervical cancer women with GH have higher sero-positive for HSV-II antibody HSV-I antigen found in the carcinoma cervicis cells The dna of HSv-l cultured in histiocyte can transform the hamster cells into cancer cells
HSV & Carcinomas cervicis Researches of recent years report that HSV-Ⅱ is associated with the development of carcinoma cervicis, here are the evidences: – Women with GH correlate with a higher incidence of cervical cancer . – women with GH have higher sero-positive for HSV-Ⅱ antibody – HSV-Ⅱ antigen found in the carcinoma cervicis cells. – The DNA of HSV-Ⅱ cultured in histiocyte can transform the hamster cells into cancer cells
Diagnosis and accessory examinations Diagnosis can be based on history of unprotected sexual contact with high-risk sexual partner(s)or history of HsV infection of partner(s) typical clinical manifestations. Differential diagnosis include chancre chancroid Behcet's syndrome Both virologic(cell culture/PCR assay)and type- specific serologic tests are of value in confirmation of the infection
Diagnosis and accessory examinations Diagnosis can be based on – history of unprotected sexual contact with high-risk sexual partner(s) or history of HSV infection of partner(s) – typical clinical manifestations. Differential diagnosis include – chancre – chancroid – Behcet’s syndrome Both virologic (cell culture / PCR assay) and typespecific serologic tests are of value in confirmation of the infection
Treatment Systemic antiviral drugs can partially control the signs oy and symptoms of herpes episodes when used to treat first clinical and recurrent episodes or when used as daily suppressive therapy Systemic antiviral drugs neither eradicate latent virus nor affect the risk, frequency, or severity of recurrences after the drug is discontinued
Treatment Systemic antiviral drugs can partially control the signs and symptoms of herpes episodes when used to treat first clinical and recurrent episodes, or when used as daily suppressive therapy. Systemic antiviral drugs neither eradicate latent virus nor affect the risk, frequency, or severity of recurrences after the drug is discontinued