病例六“”，红病史：男性，40岁，颈部患肿、热、痛，10天后局部红肿发展至手掌大，体温38℃，局部手术切开引流高热、头痛，次日体检发当晚即恶寒、现病人轻度黄疽，肝脾肿大，体温39℃WBC计数21.0G/L思考题：用所学的炎症知识，作出病理诊断并解释上述临床表现
病 例 六 病史：男性，40岁，颈部患“疖”，红、 肿、 热、痛，10天后局部红肿发展至手 掌大，体温38℃，局部手术切开引流。 当晚即恶寒、高热、头痛，次日体检发 现病人轻度黄疸，肝脾肿大，体温39℃， WBC计数21.0G/L。 思考题：用所学的炎症知识，作出病理诊 断并解释上述临床表现
Section 2. Acute inflammation.Two major defensive components:AntibodyagainstmicrobesLeukocytesThe process of exudation :Changesofhemodynamics2)Increasedvascularpermeability3)Exudation offluid andleukocytes
Section 2. Acute inflammation Two major defensive components: Antibody Leukocytes The process of exudation : 1) Changes of hemodynamics 2) Increased vascular permeability 3) Exudation of fluid and leukocytes against microbes
一.Changes ofhemodynamicsAlterationinvascularflowandcaliber1. Transient vasoconstriction of arterioles:lastingforafew seconds.2.Vasodilation andincreased blood flow1）Arteriolardilationopening of new cap beds increased blood flowinflammatoryhyperemia
一 . Changes of hemodynamics Alteration in vascular flow and caliber 1. Transient vasoconstriction of arterioles: lasting for a few seconds. 2. Vasodilation and increased blood flow (1) Arteriolar dilation opening of new cap beds increased blood flow inflammatory hyperemia
(2)Relatedtothefactorsof:Body fluid :chemical mediatorNervous:axonreflection3. Slowing of blood flow:increased permeability of the microvasculatureoutpouring of fluid into extracellular tissuesconcentration of RBC and increased viscosity of bloodstasis ofbloodflow
(2) Related to the factors of: Body fluid : chemical mediator Nervous: axon reflection 3. Slowing of blood flow: increased permeability of the microvasculature outpouring of fluid into extracellular tissues concentration of RBC and increased viscosity of blood stasis of blood flow
正常血流血管扩张血流加快血管进一步扩张血流开始变慢血浆渗出血流变慢白细胞游出血管外血流显著变慢除白细胞外红细胞亦露出血管反映和渗出模式图