Concept and Types of fr Free radicals are atoms or molecules with unpaired electrons in their outer orbital 1. Non-lipid free radicals 2. Lipid fre ee radicals
Concept and Types of FR Free radicals are atoms or molecules with unpaired electrons in their outer orbital 1. Non-lipid free radicals 2. Lipid free radicals
Reactive oxygen species( unpaired electrons 0:0 00 00 0:H :0:H Oxygen Superoxide anion Peroxide Hydroxyl radical Hydroxyl ion stable chemical free radicals oxidation antioxidant stable chemicals
Classification (1)Oxygen free radical (OFR)--Induced by 02 O pe es OH O Rective O OFR xygen Species HON (ROS peroxynitrite
(1) Oxygen free radical（OFR) ---Induced by O2 Rective Oxygen Species (ROS) OFR H2O2 Types O·- 2 OH· 1O2 Classification peroxynitrite
(2)Lipid radicals HO types: L Lipid radical LO·Aoy Initiation LOO Unsaturated lipid Propagation (3)Cl·、CH3·csm NO OOH Lipid peroxide Lipid peroxyl radical
(2) Lipid radicals types： L· LO·Alkoxyl LOO· (3) Cl·、CH3 ·(Methane )、 NO ·
1. Generation of free radical 1)Initiation 2) Propagation dEgradation
1. Generation of free radical 1) Initiation 2) Propagation 3) Degradation