Cytoplasm Integral protein Outer membrane Ribosome Inner membrane 0 Nuclear pore complex ER Intermembrane Lamina space Heterochromatin (a) Copyright 1999 John Wiley and Sons.Inc.All nights reserved
二、核孔是物质运输的通道 由至少50种不同的pr构成,称为核孔复合体 (nuclear pore complex,NPC). 般哺乳动物细胞约3000个核孔。 电镜下观察核孔呈圆形或八角形,一般认 为其结构如fish-trap。 Dr Tian 2008
二、核孔是物质运输的通道 • 由至少50种不同的pr构成,称为核孔复合体 (nuclear pore complex,NPC)。 • 一般哺乳动物细胞约3000个核孔。 • 电镜下观察核孔呈圆形或八角形,一般认 为其结构如fish-trap
Cytoplasmic face cytoplasmic particles From M.W.Goldberg and T.D.Allen,J.Cell Biol 119:1431. 1992:by copyright permission of the Rockefellor University Press
Cytoplasmic face cytoplasmic particles
Nuclear face basket inner complex From M.W.Goldberg and T.D.Allen,J.Cell Biol 119:1431, 1902:by copyright permission of the Rockefeller University Press
Nuclear face basket inner complex
The Nuclear Pore Cytoplasmic filament Central plug Cytoplasmic ring Spoke Outer nuclear membrane Nuclear Lumen envelope Inner nuclear Nuclear membrane ring Basket Nuclear basket filament Terminal ring
The Nuclear Pore