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临床医学 > 复旦大学：《内科学》课程教学资源（PPT课件讲稿）内分泌总论
复旦大学：《内科学》课程教学资源（PPT课件讲稿）内分泌总论
History and development of Endocrinology(1) Roughly a hundred years ago, Starling coined the term hormone to describe secretin, a substance secreted by the small intestine into the blood stream to stimulate pancreatic secretion. In his Croonian Lectures, Starling considered the endo- crine and nervous systems as two distinct mechanisms for coordination and control of organ function. Thus, endocrinology found its first home in the discipline of mammalian physiology.
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G-protein-coupled 7-membrane- spanning receptor extracellular adenylate plasma membrane clase cytoplasmic COOH tail G-protein intracellular loop Ill G-protein-coupled 7-membrane spanning receptor
11 G-protein-coupled 7-membrane spanning receptor
CHO (AASRGeOCOEOSONGPOGMNH2 EXTRACELLULAR SURFACE ntagonist binding MOO do G SFV POWC YI 08 L ovo swa SIT AO 8总 (XROYAXE G Pr ARXROXCOC CYTOPLASMIC (FIK SURFACE PKA Sites Phosphoryla AOGSOEGTNXGNXSSXYGN⑧A and COOH(OSONCOCNOOOSOONOSOO 12 G-protein-coupled 7-membrane spanning receptor
12 G-protein-coupled 7-membrane spanning receptor
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